Search Results - anahid+jewett

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Combination of Supercharged NK with Supercharged Gamma Delta T Cells and Supercharged CD8+ T Cells and Super Charged iNKT Cells Should Eliminate Both (UCLA Case No. 2022-322)

SUMMARY: Researchers at UCLA’s School of Dentistry have developed methods and protocols for culturing and priming various immune cells into a “supercharged” phenotype. The studied cell types include NK and iNKT cells, gamma delta T cells, and CD8+ T cells. When deployed in combination, these supercharged cells were found to eliminate...

Published: 7/19/2023 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy

2022-014 Prevention of Bone Loss With Probiotic Bacteria AJ2 and/or Super-Charged NK Cells in Cancer and Other Diseases

SUMMARY: UCLA researchers in the School of Dentistry have discovered novel therapeutic methods involving probiotic bacteria and super-charged natural killer cells that successfully prevent bone loss in pancreatic cancer, with huge therapeutic potential for other cancer types and diseases. BACKGROUND: Metabolic bone disorders are associated with several...

Published: 7/19/2023 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Orthopaedics

2021-182: COMBINING AUTOLOGOUS OR ALLOGENEIC TOTAL MONOCYTES OR CD16+ MONOCYTES TO PROTECT AND INCREASE THE EXPANSION AND FUNCTION OF STEM CELLS.

SUMMARY: UCLA researchers in the department of Dentistry have developed a novel approach to increase the successful transplantation and survival of stem cells into patients. BACKGROUND: The World Health Organization has recognized that transplantation of human cells saves and restores essential life functions to patients who are not presented with...

Published: 11/15/2024 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2021-129 USE OF COX2 KNOCK OUT MONOCYTES AND OSTEOCLASTS TO ACTIVATE AND EXPAND NK CELLS

SUMMARY: UCLA Researchers in the Department of Dentistry have developed a procedure to increase immune response in cancer patients. BACKGROUND: Natural killer (NK) cells are a type of cytotoxic lymphocyte critical to the innate immune system. NK cells provide rapid responses to viral infection and are also crucial to inhibiting tumor formation. They...

Published: 11/15/2024 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy

2006-585 DETOXIFIED AND OSTEOCONDUCTIVE BONE CEMENT

INTRO SENTENCE: UCLA researchers have developed a novel bone cement material for the treatment of osteoporotic fractures and degenerative joint disorders.BACKGROUND:Bone cement is a critical component of various types of orthopedic surgery that is used as spacers and for fixation of implants. Bone cement can be loaded with antibiotics to help with the...

Published: 9/20/2023 | Inventor(s): Takahiro Ogawa, Anahid Jewett

Keywords(s): Medical Devices and Materials, Musculoskeletal Disease

Category(s): Therapeutics > Musculoskeletal Disease

2007-347 USE OF PERIPHERAL BLOOD MONONUCLEAR CELLS TO TRIGGER DIFFERENTIATION OF MESENCHYMAL STEM CELLS AND OSTEOBLASTS

Use of Peripheral Blood Mononuclear Cells to Trigger Differentiation of Mesenchymal Stem Cells and OsteoblastsSUMMARYUCLA researchers have found that activated NK cells can lyse cancer stem cells, providing a promising approach to the prevention of disease establishment and progression.BACKGROUNDTaken as a whole, roughly half of patients receiving treatment...

Published: 7/19/2023 | Inventor(s): Anahid Jewett

Keywords(s):

Category(s): Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine

2017-400 Osteoclast Activated Super-Charged NK Cells Preferentially and Rapidly Expand CD8+ T Cells from Cancer Patients and BLT Humanized Mice

Osteoclast Activated Super-Charged NK Cells Preferentially And Rapidly Expand CD8+ T Cells From Cancer Patients And BLT Humanized MiceSUMMARYUCLA researchers in the School of Dentistry have developed a novel strategy to expand highly functional natural killer cells and to expand large number of CD8+ T cells using super-charged natural killer cells.BACKGROUNDNatural...

Published: 7/19/2023 | Inventor(s): Anahid Jewett

Keywords(s): Immunotherapy, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Therapeutics, Therapeutics > Immunology And Immunotherapy