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2020-428 CILENGITIDE AS A NEW AGENT FOR THE TREATMENT OF DYSREGULATED WOUND HEALING IN EHLERS DANLOS SYNDROME
UCLA researchers in the Department of Medicine have uncovered a new use of cilengitide for the treatment of dysregulated wound healing in Classic Ehlers-Danlos syndrome.BACKGROUND:Classic Ehlers-Danlos syndrome (cEDS) is a genetic disease that weakens the connective tissues in the body. Mutations in the Col5a1 or Col5a2 genes mean that production of...
Published: 7/19/2023
|
Inventor(s):
Arjun Deb
Keywords(s):
Cardiovascular
,
Genetic Disease
,
Therapeutics & Vaccines
Category(s):
Therapeutics > Cardiovascular
2017-443 Small Molecule Inhibitors of Cardiovascular and Renal Ectopic Calcification
Small Molecule Inhibitors of Cardiovascular and Renal Ectopic CalcificationSUMMARYUCLA researchers in the Department of Medicine have discovered that administration of small molecule inhibitors of ENPP1 or functional antagonists of PPi can substantially attenuate ectopic calcification. This suggests that ENPP1 and PPi can be potential pharmacological...
Published: 7/19/2023
|
Inventor(s):
Arjun Deb
Keywords(s):
Cardiovascular
,
Renal
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > Cardiovascular
,
Therapeutics > Renal