Search Results - renal

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New Fusion Molecule Based on Novel TAA Variant (UCLA Case No. 2007-217)

BACKGROUND: Renal cell carcinoma (RCC) affects approximately 39,000 Americans and causes an estimated 13,000 deaths per year. Metastatic RCC poses a therapeutic challenge because of its resistance to conventional modes of therapy. Approximately one third of RCC patients will present at the metastatic stage and one third of patients with localized disease...

Published: 2/16/2024 | Inventor(s): Arie Belldegrun, Zhenhua Li

Keywords(s): Cancer, Immunotherapy, Renal, Renal cell carcinoma, renal diseases

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Renal

2020-859-1 Novel Approach to Modulate Renal Neurotransmission via Percutaneous

SUMMARY: UCLA researchers in the Department of Medicine-Cardiology have developed a method that applies renal denervation to specific renal arteries to treat resistant hypertension. BACKGROUND: Sympathetic nervous system activation occurs when chemicals, such as adrenaline, bind to multiple receptors that are responsible for vital functions such...

Published: 8/2/2023 | Inventor(s): Olujimi Ajijola

Keywords(s): Artery, Blood Pressure, Hypertension, Hypertension Urine, Kidney, Medical Device, Renal, Surgery

Category(s): Life Science Research Tools, Diagnostic Markers, Medical Devices

SYNERGISM BETWEEN PROTON PUMP INHIBITORS AND A GI PEPTIDE IN REDUCING ACID SECRETION

Case 2000-093UCLA researchers in the Department of Medicine have discovered a novel method to improve the efficacy of proton pump inhibition. BACKGROUND:A vast number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease,...

Published: 7/19/2023 | Inventor(s): Joseph Pisegna

Keywords(s): Gastroenterology & Digestive Disease, Renal, Therapeutics & Vaccines

Category(s): Therapeutics > Gastroenterology, Therapeutics > Renal

Smart Dialysis Catheter

UC Case No. 2019-873SUMMARY:UCLA researchers in the Department of Cardiology at UCLA’s David Geffen School of Medicine have developed a smart dialysis catheter that can measure different patient vitals in real-time to prevent hospitalizations due to renal failure.BACKGROUND:Kidney failure currently affects 660,000 Americans. 468,000 of these individuals...

Published: 7/19/2023 | Inventor(s): Asim Rafique

Keywords(s): Bioinformatics, Cardiovascular, Diagnostic Platform Technologies (E.G. Microfluidics), Digital Health, Hospital Systems And Devices, Medical Devices and Materials, Metabolic Diseases, Monitoring And Recording Systems, Renal, Urology

Category(s): Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Cardiovascular

2017-443 Small Molecule Inhibitors of Cardiovascular and Renal Ectopic Calcification

Small Molecule Inhibitors of Cardiovascular and Renal Ectopic CalcificationSUMMARYUCLA researchers in the Department of Medicine have discovered that administration of small molecule inhibitors of ENPP1 or functional antagonists of PPi can substantially attenuate ectopic calcification. This suggests that ENPP1 and PPi can be potential pharmacological...

Published: 7/19/2023 | Inventor(s): Arjun Deb

Keywords(s): Cardiovascular, Renal, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Renal

2004-084 Adipose Derived Stem Cells for Reconstruction of the Urinary Tract

Stem Cell Urinary Tract Reconstruction TherapySUMMARYResearchers from the UCLA Department of Urology have successfully harvested stem cells from adipose tissue and differentiate them into functioning smooth muscle cells. These adipose derived stem cells can then be used for reconstruction or tissue engineering of smooth muscle containing organs, especially...

Published: 7/19/2023 | Inventor(s): Benjamin Wu, Larissa Rodriguez

Keywords(s): iPS/stem cells, Renal, Stem Cells / Regenerative Medicine, Urology

Category(s): Therapeutics > Urology, Therapeutics > Renal, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells