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Genetic Mechanisms of Resistance to Anti-PD-1/L1 (UCLA Case No. 2016-075)

Genetic Mechanisms of Resistance to Anti-PD-1/L1SUMMARYUCLA researchers have identified a rare genetic mutation in the interferon receptor signaling pathway that can be used as a diagnostic to predict whether a patient will be or has become resistant to a cancer immunotherapy.BACKGROUNDClinical responses to programmed death‐1 (PD‐1) blockade therapy...

Published: 2/10/2024 | Inventor(s): Antoni Ribas, Daniel Shin, Angel Garcia-Diaz, Blanca Homet Moreno, Jesse Zaretsky

Keywords(s): Immunotherapy, Oncology Immunotherapy, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy