Search Results - jesse+zaretsky

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Genetic Mechanisms of Resistance to Anti-PD-1/L1 (UCLA Case No. 2016-075)

Genetic Mechanisms of Resistance to Anti-PD-1/L1SUMMARYUCLA researchers have identified a rare genetic mutation in the interferon receptor signaling pathway that can be used as a diagnostic to predict whether a patient will be or has become resistant to a cancer immunotherapy.BACKGROUNDClinical responses to programmed death‐1 (PD‐1) blockade therapy...

Published: 2/10/2024 | Inventor(s): Antoni Ribas, Daniel Shin, Angel Garcia-Diaz, Blanca Homet Moreno, Jesse Zaretsky

Keywords(s): Immunotherapy, Oncology Immunotherapy, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy

Methods for Predicting Response Patterns to Anti-PD-1 Therapy in Metastatic Melanoma (UCLA Case No. 2016-582)

SUMMARYDr. Roger Lo and colleagues in the Department of Medicine at UCLA have identified a method to predict a melanoma patient’s resistance to pembrolizumab and other immune checkpoint inhibitors.BACKGROUNDImmune checkpoint inhibitors are the most recent stars in cancer therapeutics: the first 4+ drugs in the category have received breakthrough...

Published: 2/14/2024 | Inventor(s): Roger Lo, Antoni Ribas, Willy Hugo, Jesse Zaretsky

Keywords(s):

Category(s): Diagnostic Markers, Therapeutics > Oncology > Oncology Immunotherapy