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2015-390 Bispecific, OR-Gate Chimeric Antigen Receptor Responsive to CD19 and CD20

Bispecific, Or-Gate Chimeric Antigen Receptor Responsive To CD19 And CD20SUMMARYUCLA research have developed a CD19‐OR‐CD20 chimeric antigen receptor (CAR) that can trigger T‐cell activation upon detection of CD19 or CD20.BACKGROUNDConventional T‐cell therapy utilizes single‐input anti‐CD19 CAR-T cells. Multiple clinical trials have reported remarkable...

Published: 9/18/2023 | Inventor(s): Yvonne Chen, Eugenia Zah, Michael Jensen, Anne Deepika Silva-Benedict

Keywords(s): Immunotherapy, Oncology Immunotherapy

Category(s): Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy