Search Results - eugenia+zah

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Single-Chain Bispecific Chimeric Antigen Receptor Targeting BCMA and CS1 for the Treatment of Multiple Myeloma (UCLA Case No. 2018-680)

UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a single-chain bispecific chimeric antigen receptor targeting BCMA and CS1 for treating multiple myeloma. BACKGROUND: Multiple myeloma (MM) is a cancer of the plasma cells that accounts for over 30,000 new diagnoses each year, according to the American Cancer...

Published: 2/19/2025 | Inventor(s): Yvonne Chen, Eugenia Zah

Keywords(s): Hematology, Immunotherapy, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Therapeutics > Immunology And Immunotherapy, Therapeutics > Hematology

2015-390 Bispecific, OR-Gate Chimeric Antigen Receptor Responsive to CD19 and CD20

Bispecific, Or-Gate Chimeric Antigen Receptor Responsive To CD19 And CD20SUMMARYUCLA research have developed a CD19‐OR‐CD20 chimeric antigen receptor (CAR) that can trigger T‐cell activation upon detection of CD19 or CD20.BACKGROUNDConventional T‐cell therapy utilizes single‐input anti‐CD19 CAR-T cells. Multiple clinical trials have reported remarkable...

Published: 2/14/2025 | Inventor(s): Yvonne Chen, Eugenia Zah, Michael Jensen, Anne Deepika Silva-Benedict

Keywords(s): Immunotherapy, Oncology Immunotherapy

Category(s): Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy