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(XN) 2005-059 PTEN Null Cell Lines
PTEN Null Cell LinesBACKGROUNDPTEN (phsosphatase and tensin homolog deleted on chromosome 10) is a tumor suppressor gene identified to be frequently mutated/deleted in various human cancers. Besides carcinogenesis, Pten may play important roles in regulating stem cell activity, insulin action and development. PTEN is a member of the protein tyrosine...
Published: 7/19/2023
|
Inventor(s):
Hong Wu
,
Daniel Freeman
Keywords(s):
Animal Models
,
Cell Lines
,
Life Science Research Tools
,
Oncology
Category(s):
Life Science Research Tools > Animal Models
,
Life Science Research Tools > Cell Lines
,
Life Science Research Tools
,
Therapeutics > Oncology
2004-073 Murine PTEN Null Prostate Cancer Model
Murine PTEN Null Prostate Cancer ModelBACKGROUNDIn the western world, prostate cancer remains the most common malignancy and the second-leading cause of cancer-related deaths in men. The PTEN gene (phosphotase and tensin homologue deleted on chromosome 10) has been well characterized as a tumor suppressor gene, and its malfunction/deletion has been...
Published: 7/19/2023
|
Inventor(s):
Hong Wu
,
Xin Liu
,
Steve Wang
Keywords(s):
Category(s):
Life Science Research Tools