Search Results - jennifer+murphy

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2018-727 MILD AND SITE-SELECTIVE 18F-LABELING OF SMALL MOLECULES AND/OR BIOMOLECULES VIA A THIOL-REACTIVE SYNTHON

INTRO SENTENCE:UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a thiol-reactive, site-specific radiolabeling of small molecules and biomolecules for positron emission tomography (PET) molecular imaging. TITLE: Mild and site-selective 18F-labeling of small molecules and/or biomolecules via thiol-reactive synthon...

Published: 7/19/2023 | Inventor(s): Jennifer Murphy, Gaoyuan Ma

Keywords(s):

Category(s): Medical Devices > Medical Imaging > PET

2018-376 CYCLOPENTADIENE COMPOUNDS FOR USE IN BIOORTHOGONAL COUPLING REACTIONS

Cyclopentadiene Compounds For Use In Bioorthogonal Coupling ReactionsSUMMARYUCLA researchers from the Department of Chemistry and Biochemistry have discovered a class of novel reagents for bioorthogonal reactions. It is stable, dynamically reactive, and readily accessible.BACKGROUNDBioorthogonal reactions link biomolecules to traceable probes that allow...

Published: 7/19/2023 | Inventor(s): Kendall Houk, Jennifer Murphy

Keywords(s): Life Science Research Tools, Other Reagents

Category(s): Life Science Research Tools, Life Science Research Tools > Other Reagents

Combination Therapy Approach Using Novel Biguanides For Cancer Treatment

SummaryResearchers in the UCLA Departments of Molecular and Medical Pharmacology, Chemistry and Biochemistry, Surgery, and Medicine have developed novel metformin analogues which, when combined with immune checkpoint inhibitors, enhance the therapeutic benefit of these inhibitors in treating triple-negative breast cancer and other malignancies.BackgroundImmune...

Published: 7/19/2023 | Inventor(s): Michael Jung, Jennifer Murphy, Richard Pietras, Begonya Comin-Anduix, Diana Marquez Garban

Keywords(s): Drug Delivery, Genetic Disease, Immunotherapy, Life Science Research Tools, Medical Devices and Materials, Oncology, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Medical Devices, Platforms > Drug Delivery, Therapeutics, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

2015-388 Fully Automated Synthesis of 16B-[18F] Fluorodihydrotestosterone ([18F]-FDHT)

TITLE: Fully Automated Synthesis of 16β- 18F-Fluorodihydrotestosterone (18F-FDHT)SUMMARY: UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a method for the fully automated synthesis of 16β- 18F-fluorodihydrotestosterone (18F-FDHT), a probe to monitor prostate cancer. BACKGROUND: Prostate cancer is the...

Published: 7/19/2023 | Inventor(s): Jennifer Murphy, Mark Lazari

Keywords(s):

Category(s): Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > PET