Search Results - jennifer+murphy

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An 18F-Labeled Novel Brain Penetrant EGFR Inhibitor to Facilitate Clinical Development for Glioblastoma (UCLA Case No. 2022-316)

UCLA researchers led by Professors Jennifer Murphy and David Nathanson have developed 18F-labeled brain-penetrant EGFR tyrosine kinase inhibitors (TKIs) as PET tracers specifically designed for imaging glioblastoma (GBM), a highly aggressive brain cancer characterized by aberrant EGFR signaling. The 18F-labeled brain-penetrant EGFR TKI PET tracers represent...

Published: 9/12/2025 | Inventor(s): Jennifer Murphy, David Nathanson

Keywords(s):

Category(s): Therapeutics > CNS and Neurology, Medical Devices > Medical Imaging

Organometallic Gold(III) Complexes for Radiolabeling Biomolecules for Applications in Positron Emission Tomography (PET) Molecular Imaging (UCLA Case No. 2022-282)

UCLA researchers led by Professor Jennifer Murphy in the Department of Molecular and Medical Pharmacology have developed a novel platform that leverages organometallic gold(III) complexes for next-generation radiolabeling of biomolecules in PET molecular imaging. This technology is strategically positioned to meet the rapidly expanding demands of precision...

Published: 9/12/2025 | Inventor(s): Jennifer Murphy

Keywords(s):

Category(s): Medical Devices > Medical Imaging

2018-727 MILD AND SITE-SELECTIVE 18F-LABELING OF SMALL MOLECULES AND/OR BIOMOLECULES VIA A THIOL-REACTIVE SYNTHON

INTRO SENTENCE:UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a thiol-reactive, site-specific radiolabeling of small molecules and biomolecules for positron emission tomography (PET) molecular imaging. TITLE: Mild and site-selective 18F-labeling of small molecules and/or biomolecules via thiol-reactive synthon...

Published: 7/17/2025 | Inventor(s): Jennifer Murphy, Gaoyuan Ma

Keywords(s):

Category(s): Medical Devices > Medical Imaging > PET

2015-388 Fully Automated Synthesis of 16B-[18F] Fluorodihydrotestosterone ([18F]-FDHT)

TITLE: Fully Automated Synthesis of 16β- 18F-Fluorodihydrotestosterone (18F-FDHT)SUMMARY: UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a method for the fully automated synthesis of 16β- 18F-fluorodihydrotestosterone (18F-FDHT), a probe to monitor prostate cancer. BACKGROUND: Prostate cancer is the...

Published: 7/17/2025 | Inventor(s): Jennifer Murphy, Mark Lazari

Keywords(s):

Category(s): Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > PET