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A Cell-Based Seeding Assay for Huntingtin Aggregation (UCLA Case No. 2018-193)

UCLA researchers from the Department of Psychiatry has created a novel cell-based seeding assay for sensitive, specific and high throughput detection of mutant Huntingtin proteins in biological samples. BACKGROUND: Huntington’s disease (HD) is a lethal genetic disorder that is caused by mutations in the huntingtin protein (mHTT). Genetic errors...

Published: 9/20/2024 | Inventor(s): Xiangdong Yang, Chung-Ying Lee, Nan Wang

Keywords(s): Cell Lines, Cns, Diagnostic Markers & Platforms, Life Science Research Tools, Targets And Assays

Category(s): Life Science Research Tools > Cell Lines, Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics > CNS and Neurology