Search Results - natalie+boehnke

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2017-459 Noncrushable Pill Formulations

Noncrushable/Nonabusable Pill FormulationsSUMMARYUCLA researchers in the Department of Chemistry & Biochemistry have developed novel abuse-deterrent opioid formulations from elastomers that resist crushing at room temperature and upon heating or cooling. The formulation also contains a dual-enzyme responsive system whereby sequential digestion by...

Published: 7/17/2025 | Inventor(s): Heather Maynard, Samantha Paluck, Natalie Boehnke

Keywords(s): Drug Delivery, Peptide Base, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base, Therapeutics

Dual-Enzyme Responsive Peptides (UCLA Case No. 2017-446)

SUMMARY UCLA researchers in the Department of Chemistry & Biochemistry have developed a dual-enzyme responsive peptide system that requires sequential digestion by two separate enzymes for cleavage at the C-terminal position of lysine. BACKGROUND Due to their high selectivity and specificity, enzyme responsive systems are commonly used for...

Published: 2/27/2026 | Inventor(s): Heather Maynard, Natalie Boehnke

Keywords(s): Drug Delivery, Peptide Base

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base