Search Results - noninvasive

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Device and Method for Recording-Guided Neuromodulation via the Olfactory Cleft (Case No. 2026-077)

Summary: UCLA researchers in the Department of Neurology have developed a minimally invasive, recording-guided closed-loop neuromodulation device enabling transnasal access to olfactory-cleft pathways for targeted modulation of deep limbic brain circuits. Background: The olfactory bulb provides direct anatomical and functional pathways to the limbic...

Published: 5/28/2026 | Inventor(s): Kevin Bickart, Mahmoud Omidbeigi

Keywords(s): Brain, Deep Brain Stimulation, Deep Brain Stimulation Current Mirror Output Impedance, device stability, Electrical Brain Stimulation, Electrical stimulation, minimally invasive device, neural stimulation, Neuromodulation, Neurostimulation, noninvasive, non-invasive, non-invasive monitoring, Transcutaneous Electrical Nerve Stimulation

Category(s): Software & Algorithms > Bioinformatics, Therapeutics > CNS and Neurology, Software & Algorithms > Digital Health, Electrical, Life Science Research Tools, Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Neural Stimulation

Needle Clamp With Rolling Sphere (Case No. 2024-211)

Summary: UCLA researchers from the Department of Radiology have developed a novel needle-holding clamp for use during minimally invasive procedures. Background: Minimally invasive procedures are now widely used for diagnosing and treating subcutaneous and deep tissue targets. These procedures use percutaneous needle insertions rather than large incisions...

Published: 6/25/2025 | Inventor(s): David Lu

Keywords(s): femtech medical device, Invasiveness Of Surgical Procedures, Medical Device, medical device cardiac monitoring, Medical Device Poly(Methyl Methacrylate), Medical Devices and Materials, Microneedle array, minimally invasive device, minimally invasive procedures, needle guidance, needle holder, noninvasive, non-invasive, non-invasive drug monitoring, non-invasive imaging, non-invasive monitoring, Smart medical device, tissue targeting accuracy, wearable medical device, wearable medical devices

Category(s): Medical Devices, Medical Devices > Surgical Tools

Salivary Exosome (NSEV) Analysis to Elucidate Intercellular Signaling Events that Precede Pilot Fatigue (UCLA Case No. 2021-172)

Researchers at UCLA’s Department of Neurology and Drug Discovery Lab have identified a novel set of biomarkers that change based on levels of Cognitive Fatigue (CF). These biomarkers can be used to non-invasively predict and assess levels of cognitive fatigue. BACKGROUND: Cognitive fatigue (CF) is an important factor in the efficiency and safety...

Published: 7/17/2025 | Inventor(s): Bruce Teter, Whitaker Cohn, Varghese John

Keywords(s): biomarkers, cognitive fatigue, exosome, noninvasive, non-invasive

Category(s): Diagnostic Markers > Targets And Assays