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Phenotyping Single Ventricle Physiology Using Electronic Health Records (Case Nos. 2025-322 and 2025-323)
Summary: UCLA researchers have created a cutting-edge, automated phenotyping tool that harnesses electronic health records to enable rapid and precise identification of single ventricle physiology (SVP), especially in neonatal and pediatric populations. Background: Single ventricle physiology (SVP) is a rare heart condition that develops before birth...
Published: 1/6/2026
|
Inventor(s):
Kim-Lien Nguyen
,
William Hsu
,
Hang Xu
Keywords(s):
Algorithm
,
cardiac cycle
,
Cardiovascular
,
Cardiovascular Disease
,
cardiovascular diseases
,
cardiovascular monitoring
,
cardiovascular prediction
,
Computer-Aided Diagnosis
,
heart disease mitigation
,
heart support
,
medical automation technology
,
Medical Device
,
medical device
cardiac monitoring
,
Medical diagnostics
,
Medical Guideline
,
non-invasive cardiac monitoring
,
Smart
medical device
,
Software
,
Software & Algorithms
,
Software Development Tools
Category(s):
Diagnostic Markers
,
Medical Device
s
,
Medical Device
s > Cardiac
,
Medical Device
s > Monitoring And Recording Systems
Tentacle (Case No. 2025-9AH)
Summary: UCLA researchers in the Department of Surgery have developed an auto-drying surgical sponge with an integrated suction device tailored for minimally invasive procedures. Background: Minimally invasive surgery (MIS) has become the preferred standard for a wide range of medical procedures, driven by its benefits of reduced patient trauma,...
Published: 12/8/2025
|
Inventor(s):
Bryan Burt
Keywords(s):
Biomedical Engineering
,
endometriosis excision
,
General Surgery
,
Gynecologic Surgery
,
Hysterectomy
,
Laparoscopy
,
Medical Device
,
Medical Guideline
,
Medical Imaging
,
Minimally Invasive Surgery (MIS)
,
Nephrectomy, prostatectomy, cystoscopy
,
Neurosurgery/Spine
,
ovarian cyst removal
,
Robotic Surgery
,
robotic surgery application
,
Robotics
,
robotics control
,
Smart
medical device
,
Surgery
,
Surgical Instrument
,
Surgical Suture
,
surgical tool
,
Surgical Tools
,
Thoracoscopy
,
urologic procedures
,
Urologic Surgery
,
Urology
Category(s):
Medical Device
s
,
Medical Device
s > Surgical Tools
Copyright: Locally Low-Rank Image Denoising for Multi-Coil Multi-Contrast Magnetic Resonance Imaging (Case No. 2025-056)
Summary: UCLA researchers have developed a software algorithm for locally low-rank denoising that improves image quality and diagnostic reliability in multi-coil, multi-contrast MRI by correcting complex noise and preserving fine image details. Background: Magnetic resonance imaging (MRI) is a powerful, non-invasive tool widely used in both research...
Published: 12/1/2025
|
Inventor(s):
Shu-Fu Shih
,
Holden Wu
Keywords(s):
3D tissue imaging
,
AI-guided medical imaging
,
Biomedical Engineering
,
Cardiac MRI
,
Cine MRI
,
Deep learning MRI
,
DENSE MRI
,
Imaging
,
Magnetic Resonance Imaging
,
Magnetic Resonance Imaging Carotid Artery Stenosis
,
Magnetic Resonance Imaging Hypoxia (Medical)
,
Magnetic Resonance Imaging Medical Physics
,
Magnetic Resonance Imaging Microangiopathy
,
Magnetic Resonance Imaging Pathology
,
Magnetic Resonance Imaging Spin Polarization
,
Medical artificial intelligence (AI)
,
Medical Device
,
Medical Device
s and Materials
,
Medical diagnostics
,
Medical Imaging
,
MRI
,
multiparametric MRI (mpMRI)
,
radial MRI
Category(s):
Electrical > Imaging
,
Electrical > Signal Processing
,
Life Science Research Tools > Research Methods
,
Medical Device
s > Medical Imaging
,
Medical Device
s > Medical Imaging > MRI
,
Software & Algorithms > Image Processing
,
Software & Algorithms
Method and Apparatus for Improving the Signal-To-Noise Ratio in Multi-Dimensional Magnetic Resonance Imaging Data (Case No. 2025-204)
Summary: UCLA researchers have developed a software-based denoising method that makes cardiac MRI images clearer and more reliable, enabling more accurate heart function measurements without requiring longer scan times. Background: Cardiac MRI is a powerful imaging tool for assessing heart health because it can provide detailed pictures of how the...
Published: 11/13/2025
|
Inventor(s):
Xiaodong Zhong
,
Shu-Fu Shih
,
Holden Wu
,
Kim-Lien Nguyen
Keywords(s):
2D ultrasound imaging
,
3D tissue imaging
,
3D ultrasound imaging
,
AI-guided medical imaging
,
AI-guided medical intervention
,
bioimaging
,
Biologic Medical Product
,
Biomedical Engineering
,
Cardiac Magnetic Resonance Imaging
,
Image Analysis
,
Imaging
,
Magnetic Resonance Imaging
,
Magnetic Resonance Imaging Carotid Artery Stenosis
,
Magnetic Resonance Imaging Hypoxia (Medical)
,
Magnetic Resonance Imaging Medical Physics
,
Magnetic Resonance Imaging Microangiopathy
,
Magnetic Resonance Imaging Pathology
,
Magnetic Resonance Imaging Spin Polarization
,
Magnetic Resonance Imaging Unmanned Aerial Vehicle
,
Medical artificial intelligence (AI)
,
Medical Device
,
medical device
cardiac monitoring
,
Medical Device
s and Materials
,
Medical diagnostics
,
Medical Imaging
Category(s):
Medical Device
s > Cardiac
,
Medical Device
s > Medical Imaging
,
Medical Device
s > Medical Imaging > MRI
,
Software & Algorithms > Image Processing
,
Software & Algorithms
Machine Learning to Predict Physiological Age Using Features Extracted From Arterial Blood Pressure (ABP) Waveforms (Case No. 2025-264)
Summary: UCLA researchers in the Department of Anesthesiology have introduced a novel machine learning model that accurately predicts physiological aging by analyzing features extracted from patients’ arterial blood pressure (ABP) waveforms. This approach enables efficient, data-driven assessment of biological aging in clinical settings to facilitate...
Published: 12/5/2025
|
Inventor(s):
Maxime Cannesson
,
Ravi Pal
Keywords(s):
Aging
,
Anesthesiology
,
biomedical sensors
,
clinical care methodology
,
clinical decision support
,
clinical outcome
,
Clinical tool
,
Computer-Aided Diagnosis
,
consumer health products
,
Digital Health
,
digital health system
,
Fatigue (Medical)
,
Health and fitness
,
health risk assessment
,
Machine Learning
,
machine learning modeling
,
Medical Device
,
Medical diagnostics
,
Monitoring (Medicine)
,
personalized medicine
,
Preventive Medicine
,
public health monitoring
,
Smart
medical device
,
Structural health monitoring
,
Telemedicine
Category(s):
Diagnostic Markers
,
Diagnostic Markers > Aging
,
Life Science Research Tools
,
Medical Device
s
Broad-Band Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Neuropsychiatric Disorders (Case No. 2025-99J)
Summary: Researchers in UCLA's Semel Institute and Department of Psychiatry have developed an innovative approach to treating depression by optimizing repetitive Transcranial Magnetic Stimulation (rTMS), improving its effectiveness for the treatment of Major Depressive Disorder (MDD) and possibly diseases of the mind and brain. Background: Depression...
Published: 10/16/2025
|
Inventor(s):
Andrew Leuchter
,
Juliana Corlier
,
Thomas Valles
Keywords(s):
Bioelectromagnetics
,
Brain
,
Deep Brain Stimulation
,
Electrical Brain Stimulation
,
energy-efficient
,
frequency modulation
,
Magnetic Field
,
Medical Device
,
medication efficacy
,
neural information
,
neural network
,
neural networks
,
neural signals
,
neural stimulation
,
neurobehavioral impairment
,
Neurocognitive
,
neurological disorders
,
Neuromodulation
,
Neuron
,
neurons
,
neuroscience
,
Neurostimulation
,
pulsed load modulation
,
therapy
,
treatment efficacy
Category(s):
Medical Device
s
,
Medical Device
s > Neural Stimulation
,
Life Science Research Tools
,
Therapeutics > CNS and Neurology
,
Therapeutics
A Denoising Technique for Multi-Contrast Multi-Coil Magnetic Resonance Imaging (Case No. 2024-233)
Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel MRI denoising technique that enhances image clarity, sensitivity, and precision by significantly reducing distortion and noise. Background: Magnetic resonance imaging (MRI) is critical for medical diagnosis, but image quality depends on achieving a high signal-to-noise...
Published: 12/15/2025
|
Inventor(s):
Holden Wu
,
Shu-Fu Shih
,
Zhaohuan Zhang
Keywords(s):
Cardiac Magnetic Resonance Imaging
,
Image Processing
,
Magnetic Resonance Imaging
,
Magnetic Resonance Imaging Carotid Artery Stenosis
,
Magnetic Resonance Imaging Hypoxia (Medical)
,
Magnetic Resonance Imaging Medical Physics
,
Magnetic Resonance Imaging Pathology
,
Medical Device
,
medical device
cardiac monitoring
,
Medical Device
s and Materials
,
Medical diagnostics
,
Medical Imaging
,
MRI
,
multi-contrast imaging
,
Signal-To-Noise Ratio
Category(s):
Medical Device
s
,
Medical Device
s > Medical Imaging
,
Medical Device
s > Monitoring And Recording Systems
,
Medical Device
s > Medical Imaging > MRI
Intrastromal Lamellar Keratoprosthesis (Artificial Cornea) (Case No. 2025-177)
Summary: UCLA researchers in the Department of Ophthalmology have developed an intrastromal artificial cornea implant designed to enhance biointegration and effectively restore vision. Background: Corneal opacities are among the top five causes of blindness worldwide. For patients who are not candidates for conventional corneal transplantation, keratoprosthesis...
Published: 7/25/2025
|
Inventor(s):
Seyed Reza Ghaffari Dehkharghani
,
Anthony Aldave
Keywords(s):
Biologic Medical Product
,
Biomedical Engineering
,
biomedical implantation
,
biomedical sensors
,
diseases of the eye
,
eye disease
,
eye motion
,
eye movement disorders
,
Eye Surgery
,
eye tracking
,
Glaucoma
,
macular corneal dystrophy
,
Macular Degeneration
,
Medical Device
,
Medical Imaging Eyepiece
,
on-eyelid sensor
,
Ophthalmic antibiotics
,
Ophthalmology
,
Other Polymers
,
Polymers
,
Prosthetics
,
Transplant
,
Transplant Rejection
,
transplant surgery
Category(s):
Medical Device
s
,
Medical Device
s > Surgical Tools
,
Therapeutics > Ophthalmology
Mechanical Cutaneous Nerve Stimulation for Reducing Epileptic Seizures and Perceived Pain (Case No. 2016-686-3)
Summary: UCLA researchers have developed a novel, non-invasive pain management device that uses mechanical vibrations to activate cutaneous sensory fibers, reducing epileptic seizures, masking pain perception and alleviating associated symptoms. Background: Unexpected death due to epilepsy is a pressing concern, with an estimated incidence of 1.2...
Published: 7/29/2025
|
Inventor(s):
Ronald Harper
,
Eberhardt Sauerland
,
Christopher Degiorgio
Keywords(s):
low-power device
,
Medical Device
,
Medical Device
s and Materials
,
minimally invasive device
,
Neuropathology
,
Neurostimulation
,
non-invasive
,
Pain Treatment
,
sample-to-answer devices
,
Semiconductor Device
,
Smart
medical device
,
Stroke
,
Transcutaneous Electrical Nerve Stimulation
,
Vibration monitoring
,
Vibration sensing
,
wearable
medical device
,
wearable
medical device
s
Category(s):
Medical Device
s
,
Medical Device
s > Monitoring And Recording Systems
,
Medical Device
s > Neural Stimulation
,
Medical Device
s > Hospital Systems
,
Therapeutics
,
Therapeutics > CNS and Neurology
A Dynamic and Adaptive Approach for Resolving Motion (Case No. 2024-250)
Summary: UCLA researchers in the Department of Radiology have developed a novel method to capture time-varying and irregular cardiac motion, producing high-precision, high-quality cine images. Background: Cine MRI is a specialized imaging technique that captures motion through a series of images, often used to evaluate cardiac function and morphology....
Published: 12/16/2025
|
Inventor(s):
Zhengyang Ming
,
Dan Ruan
,
Anthony Christodoulou
,
Kim-Lien Nguyen
Keywords(s):
arrhythmia
,
Biomonitoring
,
Cardiac Magnetic Resonance Imaging
,
cardiovascular diseases
,
cardiovascular monitoring
,
Image Resolution
,
Imaging
,
Magnetic Resonance Imaging
,
Medical Device
,
medical device
cardiac monitoring
,
Medical Imaging
,
Monitoring And Recording Systems
,
MRI
,
non-invasive cardiac monitoring
,
optimization
Category(s):
Medical Device
s
,
Medical Device
s > Cardiac
,
Medical Device
s > Medical Imaging
,
Medical Device
s > Medical Imaging > MRI
,
Medical Device
s > Monitoring And Recording Systems
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