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2017-645 HUMANIZED ANTIBODIES TO THE EXTRACELLULAR DOMAINS OF HUMAN N-CADHERIN

UCLA researchers in the Department of Molecular and Medical Pharmacology have developed humanized antibody therapies for invasive prostate and bladder cancers that express N-cadherin.BACKGROUNDProstate cancer is the second leading cause of cancer death among men in the United States (National Cancer Institute). Unfortunately, systemic therapies such...

Published: 3/8/2024 | Inventor(s): Anna Wu, Robert Reiter, Kirstin Zettlitz

Keywords(s): Antibodies, Antibody Delivery Platforms, Diagnostic Markers & Platforms, Drug Delivery, Gastroenterology & Digestive Disease, Life Science Research Tools, Nucleic Acids, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Diagnostic Markers, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Therapeutics, Therapeutics > Gastroenterology, Platforms > Drug Delivery > Nucleic Acids

Antibody Therapy for Inhibiting Bladder Cancer and Prostate Cancer Metastasis

Case 2005-098UCLA has a robust intellectual property position on antibody-based diagnostics and therapeutics against N-cadherin for the treatment and detection of prostate and bladder cancers. The research and development leading to this promising technology has been conducted by Dr. Robert Reiter, Professor of Urology and Director of UCLA’s Prostate...

Published: 7/19/2023 | Inventor(s): Robert Reiter

Keywords(s): Antibodies, Immunotherapy, Oncology, Oncology (Small Molecules, Peptides and Antibodies), Oncology Immunotherapy, Therapeutics & Vaccines

Category(s): Life Science Research Tools > Antibodies, Therapeutics, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology > Oncology (Small Molecules)

Antibody Therapy for Inhibiting Bladder Cancer and Prostate Cancer Metastasis

Case 2008-551UCLA has a robust intellectual property position on antibody-based diagnostics and therapeutics against N-cadherin for the treatment and detection of prostate and bladder cancers. The research and development leading to this promising technology has been conducted by Dr. Robert Reiter, Professor of Urology and Director of UCLA’s Prostate...

Published: 7/19/2023 | Inventor(s): Robert Reiter, Zev Wainberg

Keywords(s): Antibodies, Oncology, Oncology (Small Molecules, Peptides and Antibodies), Oncology Immunotherapy, Therapeutics & Vaccines

Category(s): Life Science Research Tools > Antibodies, Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology > Oncology (Small Molecules)