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Search Results - targeted+therapy
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Subgraph Matching for High-Throughput DNA-Aptamer Secondary Structure Classification and Machine Learning Interpretability (Case No. 2025-104)
Intro Sentence: UCLA researchers in the Department of Mathematics have developed machine learning methods to rapidly identify novel aptamer sequences for target binding to accelerate highly-accurate diagnostic and therapeutic development. Background: Aptamers are single-stranded nucleotide polymers that bind with high affinity to targets such as...
Published: 7/22/2025
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Inventor(s):
Andrea Bertozzi
,
Anne Andrews
,
Matthew Tyler
,
Paolo Climaco
,
Noelle Mitchell
Keywords(s):
Advanced Computing / AI
,
advanced computing methods
,
Aptamers
,
Artifical Intelligence (Machine Learning, Data Mining)
,
artificial intelligence/machine learning models
,
bioinformatics pipeline
,
cancer target
,
clustering
,
computational efficiency
,
computational efficiency and analysis
,
design software
,
DNA clustering
,
DNA oligomer
,
DNA Sequencing
,
Drug
,
Drug Delivery
,
Drug Development
,
Drug Discovery
,
drug screening
,
high throughput
,
high throughput assays
,
high throughput testing
,
high-throughput analysis
,
High-Throughput Screening
,
interpretability, pipeline
,
large-scale parallelization
,
Machine Learning
,
machine learning modeling
,
motif structures
,
open source
,
open source code
,
OpenAI
,
Pharmaceutical Drug
,
protein classification
,
secondary structure
,
SELEX
,
sequences of interest
,
single strand DNA sequences
,
Software
,
Software & Algorithms
,
Software Development Tools
,
Software-enabled learning
,
subgraph matching
,
target binding
,
target detection
,
Targeted Therapy
,
Targets And Assays
,
tissue targeting accuracy
Category(s):
Software & Algorithms
,
Software & Algorithms > AI Algorithms
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Software & Algorithms > Data Analytics
,
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Life Science Research Tools > Screening Libraries
,
Platforms
,
Platforms > Drug Delivery
,
Diagnostic Markers > Targets And Assays
,
Diagnostic Markers
,
Software & Algorithms > Bioinformatics
A Novel “Host-Guest”-Based Supramolecular Hydrogel for Dental Pulp Regeneration (Case No. 2023-154)
Summary: Researchers in the Department of Dentistry at UCLA have developed an innovative hydrogel for a vast array of biomedical and tissue engineering applications. Background: Hydrogels have emerged as powerful tools in biomedical engineering due to their ability to provide a supportive environment for cell growth, tissue repair, and drug delivery....
Published: 4/29/2025
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Inventor(s):
Alireza Moshaverinia
,
Weihao Yuan
Keywords(s):
anti-dehydration
,
Drug Delivery
,
dynamic identification
,
hydrogel
,
Stem Cells / Regenerative Medicine
,
Targeted Therapy
,
tissue regeneration
Category(s):
Chemical
,
Materials > Functional Materials
,
Platforms > Drug Delivery
,
Platforms > Drug Delivery > Antibody Delivery Platforms
,
Platforms > Drug Delivery > Nanoparticles
,
Platforms > Drug Delivery > Viral Delivery Systems
,
Therapeutics > Cell Therapy
,
Therapeutics > Medication
,
Therapeutics > Stem Cells And Regenerative Medicine
A Novel Device to Produce Autologous Serum Eye Drops at the Point of Care (Case No. 2021-198)
SUMMARY: UCLA researchers in the Stein and Doheny Eye Institutes have designed a device that can produce autologous serum eye drops at the point-of-care, greatly reducing the cost and complexity of the production process. BACKGROUND: Ocular surface diseases afflict hundreds of millions of people per year worldwide. Autologous serum eye drops benefit...
Published: 7/17/2025
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Inventor(s):
Justin Karlin
Keywords(s):
Human Serum Albumin
,
Medical Devices and Materials
,
Targeted Therapy
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools > Lab Equipment
,
Therapeutics > Ophthalmology