Search Results - aptamers

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Enzyme-Based Method for the Amplified Detection of Molecules on Particles (Case No. 2026-130)

Summary: UCLA researchers in the Department of Bioengineering have developed a novel enzyme-based particle platform that enables amplified molecular detection in fully aqueous systems for sensitive, multiplexed analysis of low-abundance analytes. Background: The detection of molecules and determination of enzymatic activity are foundational across...

Published: 6/15/2026 | Inventor(s): Alyssa Arnheim, Dino Di Carlo

Keywords(s): Antibody, Aptamers, Assay, barcode, Biomarker, Biosensor, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Drug Discovery, ELISA, enzyme functionalization, Enzyme Substrate (Biology), Flow Cytometry, Fluorescence, High-Throughput Screening, hydrogel, Immunoassay, Medical diagnostics, microparticles, Molecular Biology, multiplexed analysis, multiplexing, Nucleic Acids, protein, Signal-To-Noise Ratio

Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers, Platforms > Diagnostic Platform Technologies, Chemical > Chemical Sensors, Life Science Research Tools > Antibodies

Subgraph Matching for High-Throughput DNA-Aptamer Secondary Structure Classification and Machine Learning Interpretability (Case No. 2025-104)

Intro Sentence: UCLA researchers in the Department of Mathematics have developed machine learning methods to rapidly identify novel aptamer sequences for target binding to accelerate highly-accurate diagnostic and therapeutic development. Background: Aptamers are single-stranded nucleotide polymers that bind with high affinity to targets such as...

Published: 8/19/2025 | Inventor(s): Andrea Bertozzi, Anne Andrews, Matthew Tyler, Paolo Climaco, Noelle Mitchell

Keywords(s): Advanced Computing / AI, advanced computing methods, Aptamers, Artifical Intelligence (Machine Learning, Data Mining), artificial intelligence/machine learning models, bioinformatics pipeline, cancer target, clustering, computational efficiency, computational efficiency and analysis, design software, DNA clustering, DNA oligomer, DNA Sequencing, Drug, Drug Delivery, Drug Development, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, interpretability, pipeline, large-scale parallelization, Machine Learning, machine learning modeling, motif structures, open source, open source code, OpenAI, Pharmaceutical Drug, protein classification, secondary structure, SELEX, sequences of interest, single strand DNA sequences, Software, Software & Algorithms, Software Development Tools, Software-enabled learning, subgraph matching, target binding, target detection, Targeted Therapy, Targets And Assays, tissue targeting accuracy

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Data Analytics, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Screening Libraries, Platforms, Platforms > Drug Delivery, Diagnostic Markers > Targets And Assays, Diagnostic Markers, Software & Algorithms > Bioinformatics