Search Results - therapeutics+%3e+gastroenterology

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Creation of a Specified Probiotic Blend to Help with Weight Loss and Associated Metabolic Disease (UCLA Case No. 2023-258)

UCLA researchers in the Department of Medicine, Vatche and Tamar Manoukin Division of Digestive Diseases have developed a novel probiotic blend composed of two gut bacteria strains. This blend has the potential to be a safe supplement for treating food addiction, obesity, cognition, and other associated metabolic diseases in humans. BACKGROUND: Obesity...

Published: 11/18/2024 | Inventor(s): Arpana Church

Keywords(s): bacterial strain, brain reward system, brain-gut microbiome, food addiction, food metabolism, gut-brain axis, Mental health, Metabolic Diseases, Nutraceuticals / Probiotics, nutritional supplement, obesity

Category(s): Therapeutics > Metabolism And Endocrinology, Therapeutics > Gastroenterology, Therapeutics > Psychiatry And Mental Health

Compounds for Improved Psychological and Resilience Measures Associated with Physical Activity (UCLA Case No. 2022-272)

UCLA researchers from the Department of Medicine have identified microbiome and metabolic markers associated with high physical activity in an obese population, leading to possible therapies that may provide the positive effects of physical activity. BACKGROUND: It is known that physical activity has a multitude of beneficial effects on health. On...

Published: 11/18/2024 | Inventor(s): Arpana Church

Keywords(s): Bacteria, Exercise, Gastroenterology & Digestive Disease, gut-brain axis, Human Gastrointestinal Tract, metabolomics, microbiome, MRI, Nutraceuticals / Probiotics, obesity, physical activity, prebiotics, Psychology

Category(s): Therapeutics > Gastroenterology, Therapeutics > Psychiatry And Mental Health, Therapeutics > Metabolism And Endocrinology

Dissecting Microbiota-Gut-Brain Interactions for the Anti-Seizure Effects of the Ketogenic Diet (UCLA Case No. 2025-006)

UCLA researchers from the Department of Integrative Biology & Physiology have identified specific components of ketogenic diets that alter the microbiome and improve seizure resistance, providing valuable data to optimize diet treatments for refractory epilepsy. BACKGROUND: Refractory epilepsy, a disease characterized by uncontrolled seizures,...

Published: 9/19/2024 | Inventor(s): Elaine Hsiao

Keywords(s): diet, dietary fiber, Epilepsy, gut, gut-brain axis, ketogenic diet, microbiome, pediatrics, seizure

Category(s): Therapeutics > Gastroenterology, Therapeutics > CNS and Neurology, Therapeutics > Metabolism And Endocrinology

Surgical Mesh Permanent Implant (Case No. 2023-109)

Summary: UCLA Researchers in the Department of Chemistry and Biochemistry have developed a bacterial nanocellulose (BNC) that exhibits promising biocompatibility and mechanical properties that can be used as a long-term treatment for medical conditions requiring surgical mesh devices. Background: Surgical mesh devices are medical devices used to...

Published: 10/7/2024 | Inventor(s): Paul Weiss, Melina Mastrodimos, Maryam Badv

Keywords(s): Biologic Medical Product, Biomedical Engineering, biomedical implantation, Implant (Medicine), Medical Device, Medical Devices and Materials, Orthopedics and Prosthetics (O & P), Prosthesis, Prosthetics, Smart medical device, Surgical Instrument, surgical mesh, Surgical Tools, wearable medical device

Category(s): Medical Devices, Medical Devices > Surgical Tools, Materials, Materials > Functional Materials, Therapeutics, Therapeutics > Gastroenterology, Therapeutics > Urology, Therapeutics > Transplant

SYNERGISM BETWEEN PROTON PUMP INHIBITORS AND A GI PEPTIDE IN REDUCING ACID SECRETION

Case 2000-093UCLA researchers in the Department of Medicine have discovered a novel method to improve the efficacy of proton pump inhibition. BACKGROUND:A vast number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease,...

Published: 7/19/2023 | Inventor(s): Joseph Pisegna

Keywords(s): Gastroenterology & Digestive Disease, Renal, Therapeutics & Vaccines

Category(s): Therapeutics > Gastroenterology, Therapeutics > Renal

2013-778 MicroRNA Biomarkers and Therapeutic Targets for Colon Cancer and IBD

Summary Researchers at the UCLA Geffen School of Medicine have identified a novel set of biomarkers consisting of a microRNA and aftiphilin (AFTPH) as an effective means to distinguish between tissues with colon cancer and normal tissues. Other biomarkers within the set are linked specifically with inflammatory bowel disease. Background Colon cancer...

Published: 7/19/2023 | Inventor(s):

Keywords(s):

Category(s): Therapeutics > Gastroenterology

2019-519 MICROBIOME-BASED MODULATION OF SENSORY NEURONAL ACTIVITY

UCLA researchers in the Department of Integrative Biology and Physiology have begun to elucidate the molecular pathways for communication between the gut microbiota and the brain, serving as potential therapeutic targets for the treatment of various neurological diseases.BACKGROUND: The gut microbiota is recognized as an important regulator of brain...

Published: 7/16/2024 | Inventor(s): Elaine Hsiao

Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease

Category(s): Therapeutics > Gastroenterology

2019-520 MATERNAL GUT MICROBIOTA REGULATION OF NEURODEVELOPMENT AND ADULT SENSORY BEHAVIOR

UCLA Researchers in the Department of Integrative Biology and Physiology have determined the necessary role for maternal gut microbes in neurodevelopment and that select microbes may prevent abnormal neurodevelopmental phenotypes.BACKGROUND: The gastrointestinal tract and brain are intimately linked, and in the past decade there have been increasing...

Published: 2/16/2024 | Inventor(s): Elaine Hsiao, Helen Vuong

Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease

Category(s): Therapeutics > Gastroenterology

2000-093 Novel Diuretic and Inhibitor of Gastric Acid Secretion

Background A wide number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease, duodenalulcers, atrophic gastritis, esophagitis, and the like. Conditions such as ZES and peptic ulcers, in particular, can have serious complications...

Published: 7/19/2023 | Inventor(s):

Keywords(s):

Category(s): Therapeutics > Gastroenterology

2018-920 INTRA-PROCEDURE IMAGE-BASED FLOW QUANTIFICATION (FOR TREATMENT EVALUATION)

INTRODUCTION:UCLA researchers in the Department of Radiology have developed a new method for analyzing portal vein blood blow at transjugular intrahepatic portosystemic shunt (TIPS) creation.BACKGROUND:TIPS creation is a common interventional method for the treatment of portal hypertension. However, post-procedure complications can arise, which often...

Published: 7/19/2023 | Inventor(s):

Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease, Life Science Research Tools, Research Methods

Category(s): Life Science Research Tools > Research Methods, Therapeutics > Gastroenterology

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