Search Results - therapeutics+%3e+renal

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New Fusion Molecule Based on Novel TAA Variant (UCLA Case No. 2007-217)

BACKGROUND: Renal cell carcinoma (RCC) affects approximately 39,000 Americans and causes an estimated 13,000 deaths per year. Metastatic RCC poses a therapeutic challenge because of its resistance to conventional modes of therapy. Approximately one third of RCC patients will present at the metastatic stage and one third of patients with localized disease...

Published: 2/16/2024 | Inventor(s): Arie Belldegrun, Zhenhua Li

Keywords(s): Cancer, Immunotherapy, Renal, Renal cell carcinoma, renal diseases

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Renal

SYNERGISM BETWEEN PROTON PUMP INHIBITORS AND A GI PEPTIDE IN REDUCING ACID SECRETION

Case 2000-093UCLA researchers in the Department of Medicine have discovered a novel method to improve the efficacy of proton pump inhibition. BACKGROUND:A vast number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease,...

Published: 7/19/2023 | Inventor(s): Joseph Pisegna

Keywords(s): Gastroenterology & Digestive Disease, Renal, Therapeutics & Vaccines

Category(s): Therapeutics > Gastroenterology, Therapeutics > Renal

2017-443 Small Molecule Inhibitors of Cardiovascular and Renal Ectopic Calcification

Small Molecule Inhibitors of Cardiovascular and Renal Ectopic CalcificationSUMMARYUCLA researchers in the Department of Medicine have discovered that administration of small molecule inhibitors of ENPP1 or functional antagonists of PPi can substantially attenuate ectopic calcification. This suggests that ENPP1 and PPi can be potential pharmacological...

Published: 7/19/2023 | Inventor(s): Arjun Deb

Keywords(s): Cardiovascular, Renal, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Renal

2004-084 Adipose Derived Stem Cells for Reconstruction of the Urinary Tract

Stem Cell Urinary Tract Reconstruction TherapySUMMARYResearchers from the UCLA Department of Urology have successfully harvested stem cells from adipose tissue and differentiate them into functioning smooth muscle cells. These adipose derived stem cells can then be used for reconstruction or tissue engineering of smooth muscle containing organs, especially...

Published: 7/19/2023 | Inventor(s): Benjamin Wu, Larissa Rodriguez

Keywords(s): iPS/stem cells, Renal, Stem Cells / Regenerative Medicine, Urology

Category(s): Therapeutics > Urology, Therapeutics > Renal, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells