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Small molecule sAPPalpha enhancers that inhibit brain p-Tau as a therapeutic for Alzheimer’s Disease (UCLA Case No. 2025-163)
Contact UCLA Technology Development Group to learn more.
Published: 9/18/2025
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Inventor(s):
Varghese John
,
Dongwook Wi
,
Jesus Campagna
Keywords(s):
Category(s):
Therapeutics > CNS and Neurology
Discrete Approximation of Permanent Magnet Arrays (Case No. 2025-203)
Summary: UCLA researchers have created a cost-effective method to prototype complex magnet arrays using simple cube magnets and 3D-printed supports, enabling faster and safer development of advanced robotic, medical, and mechatronic systems. Background: Permanent magnets are widely used in mechatronic systems, such as motors, robotic grippers, medical...
Published: 12/23/2025
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Inventor(s):
Tyler Clites
,
He Kai Lim
,
Will Flanagan
,
Cameron Taylor
Keywords(s):
Category(s):
Materials
,
Materials > Functional Materials
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Medical Devices
,
Mechanical
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Mechanical > Robotics
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Platforms
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Platforms > Drug Delivery
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Medical Devices > Medical Imaging
,
Life Science Research Tools
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Life Science Research Tools > Research Methods
A Potent Short Hairpin RNA (SHRNA734) to Positively Select and Eliminate Genetically Modified Cells (UCLA Case No. 2016-524)
BACKGROUND: Gene therapy strategies to modify human stem cells hold great promise for curing many human diseases. However, previous clinical studies have met with limited success, largely due to the low engraftment of gene modified stem cells. One strategy to overcome this challenge involves engineering stem cells in which HPRT expression is knocked...
Published: 12/2/2025
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Inventor(s):
Dong Sung An
,
Saki Shimizu
Keywords(s):
Category(s):
Therapeutics > Gene Therapy And Editing
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Therapeutics > Infectious Diseases