Search Results - april+pyle

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2017-701 Nanoparticle-Enabled Delivery of Large Plasmid DNA for Gene Therapy of Duchenne Muscular Dystrophy and Cancer

Polyrotaxane Nanoparticles for Delivery of Large Plasmid DNA in Duchenne Muscular DystrophySUMMARYUCLA researchers have designed, synthesized, and validated a polyrotaxane nanocarrier for targeted delivery of large plasmids for gene therapy applications for treatment of Duchenne muscular dystrophy and cancer.BACKGROUNDRapid development of genome/epigenome...

Published: 7/19/2023 | Inventor(s): Melissa Spencer, April Pyle, Huan Meng, Courtney Young, Xiangsheng Liu

Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Genetic Disease, Life Science Research Tools, Medical Devices and Materials, Musculoskeletal Disease, Nanoparticles, Oncology, PEG, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Medical Devices, Platforms > Drug Delivery, Therapeutics, Therapeutics > Gene Therapy And Editing, Therapeutics > Musculoskeletal Disease, Platforms > Drug Delivery > Nanoparticles, Therapeutics > Oncology, Platforms > Drug Delivery > PEG

2017-217 Three-step Method for Universal Enrichment, Expansion, and Maturation of Skeletal Muscle Cells Derived from Human Pluripotent Stem Cells

Three-Step Method For Universal Enrichment, Expansion, And Maturation Of Skeletal Muscle Cells Derived From Human Pluripotent Stem CellsSUMMARYUCLA researchers have developed a novel method for enriching, expanding, and maturing populations of skeletal muscle progenitor cells (SMPCs) from human pluripotent stem cells (hPSCs).BACKGROUNDSkeletal muscle...

Published: 7/19/2023 | Inventor(s): April Pyle, Michael Hicks

Keywords(s): Cell Lines, Gene Therapy, iPS/stem cells, Life Science Research Tools, Musculoskeletal Disease, Research Methods, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Lines, Therapeutics, Therapeutics > Musculoskeletal Disease, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells, Therapeutics > Gene Therapy And Editing