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2016-290 TRANSIENT EXPRESSION OF BCL-2 TO AMELIORATE CYTOTOXICITY OF GENE MODIFICATION REAGENTS IN STEM CELLS.

Transient Expression Of BCL-2 To Ameliorate Cytotoxicity Of Gene Modification Reagents In Stem CellsSUMMARYResearchers at the UCLA Department of Microbiology, Immunology and Molecular Genetics have developed methods for efficient gene editing in stem cells by increasing the level of apoptosis regulator BCL-2.BACKGROUNDEngineered nucleases, such as zinc...

Published: 7/19/2023 | Inventor(s): Donald Kohn, Carmen Bjurstroem

Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Platforms > Drug Delivery, Therapeutics, Therapeutics > Gene Therapy And Editing