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PAK4 in Cancer Immune Exclusion
Case 2018-209Researchers at the UCLA David Geffen School of Medicine have proposed that T cell tumor infiltration and the anti-tumor activity of anti-PD-1/PD-L1-based immunotherapy to be modulated through kinase PAK4 activity. BACKGROUNDThe p21-activated kinase 4 (PAK4) is a member of the PAK family of serine/threonine kinases, which are important...
Published: 7/19/2023
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Inventor(s):
Antoni Ribas
,
Catherine Grasso
Keywords(s):
Immunotherapy
,
Life Science Research Tools
,
Medical Devices and Materials
,
Oncology
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Medical Devices
,
Therapeutics
,
Therapeutics > Immunology And Immunotherapy
,
Therapeutics > Oncology