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Interferon Activation Score Is a Biomarker for Immunotherapy in Malignant Glioma Patients (UCLA Case No. 2024-043)
UCLA researchers from the Department of Neurosurgery have characterized immune responses in malignant glioma patients receiving immunotherapy to develop a robust biomarker that will allow prediction of clinical outcomes following treatment. BACKGROUND: Malignant gliomas are the most common primary brain tumors in adults. No cures exist and most gliomas...
Published: 10/23/2024
|
Inventor(s):
Robert Prins
Keywords(s):
adjuvant therapy
,
Biomarker
,
Chemotherapy
,
Clinical Trial
,
dendritic cell vaccination
,
Glioblastoma
,
Glioma
,
immune response
,
Immunotherapy
,
interferon
,
malignant glioma
Category(s):
Diagnostic Markers > Immunology
,
Diagnostic Markers > Cancer
,
Therapeutics > Inflammation And Inflammatory Diseases
,
Therapeutics > Oncology
,
Therapeutics > CNS and Neurology
Copyright: A Comprehensive Platform to Shorten the Period Required for Vaccine
Clinical Trial
(Case No. 2024-148)
Summary: UCLA researchers have developed a software to accelerate vaccine
clinical trial
processes by modeling disease behavior and targeting future trial participants. Background: Vaccine clinical trials are time-intensive processes; ones that may be necessary during active pandemics in which time is of short supply. One of the primary factors contributing...
Published: 11/15/2024
|
Inventor(s):
Akihiro Nishi
Keywords(s):
Bioinformatics
,
Clinical Trial
,
Live attenuated vaccine
,
Public Health
,
Simulation & Modeling
,
Software & Algorithms
,
Therapeutics & Vaccines
,
Vaccines
Category(s):
Software & Algorithms > Statistical Models
,
Software & Algorithms > Bioinformatics
A Process for Identifying Health Modifying Interventions Through Epigenetic Prediction (Case No. 2023-107)
Summary: UCLA researchers in the Department of Neurology have developed a novel method that leverages epigenetic markers to identify recommended and necessary health interventions. Background: Disease risk prediction and intervention involves identifying individuals or populations with a higher likelihood of developing a particular condition based...
Published: 3/22/2024
|
Inventor(s):
Noah Zaitlen
,
Eran Halperin
,
Elior Rahmani
,
Michael Thompson
,
Zeyuan (Johnson) Chen
Keywords(s):
Clinical decision support system
,
clinical outcome
,
Clinical Trial
,
disease outcome
,
Epigenetics
,
health risk assessment
,
outcome probability
,
patient outcome
,
prognostic
,
Public Health
,
public health monitoring
,
Risk Assessment
,
risk reduction
,
risk score
,
Simulation & Modeling
,
statistical modeling
,
treatment efficacy
Category(s):
Software & Algorithms
,
Software & Algorithms > Data Analytics
,
Software & Algorithms > Digital Health
,
Software & Algorithms > Statistical Models
,
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
2022-231 Synthetic Generation of Face Videos with Plethysmograph Physiology
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a method to avoid expensive
clinical trial
s by generating synthetic face videos. Background: Healthcare providers have increased their use of virtual diagnostic tools during the COVID-19 pandemic. These tools have allowed patients to undergo basic...
Published: 11/15/2024
|
Inventor(s):
Achuta Kadambi
,
Laleh Jalilian
,
Zhen Wang
,
Yunhao Ba
,
Pradyumna Chari
,
Oyku Bozkurt
Keywords(s):
Artificial Intelligence
,
Blood Pressure
,
Cardiac Electrophysiology
,
Circulatory System
,
Clinical Trial
,
Heart Rate
,
Remote Sensing
,
Surgical Instrument Optical Coherence Tomography
,
Telemedicine
Category(s):
Software & Algorithms > Digital Health
,
Electrical > Imaging
,
Software & Algorithms > Communication & Networking
,
Medical Devices
,
Medical Devices > Medical Imaging
,
Medical Devices > Monitoring And Recording Systems