Search Results - chemotherapy

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Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)

Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...

Published: 8/21/2025 | Inventor(s): Wentai Liu

Keywords(s): algorithmic cancer detection, Bladder Cancer, blood cancers, Brain cancer, Breast Cancer, Cancer, cancer antigen, cancer detection, Cancer Immunotherapy, cancer inhibition, cancer metabolism, Cancer stem cells, cancer target, castration resistant prostate cancer, Chemotherapy, head and neck cancer, lympathic cancers, lymphatic cancer, Mesenchymal Stem Cell Derived Cancer Cells, Neuromodulation, non-small cell lung cancer, Orthotopic cancer models, Pancreatic cancer, prostate cancer, small cell cancer, small cell lung cancer, small cell prostate cancer

Category(s): Medical Devices, Medical Devices > Neural Stimulation, Chemical, Electrical, Therapeutics, Therapeutics > Oncology

Interferon Activation Score Is a Biomarker for Immunotherapy in Malignant Glioma Patients (UCLA Case No. 2024-043)

UCLA researchers from the Department of Neurosurgery have characterized immune responses in malignant glioma patients receiving immunotherapy to develop a robust biomarker that will allow prediction of clinical outcomes following treatment. BACKGROUND: Malignant gliomas are the most common primary brain tumors in adults. No cures exist and most gliomas...

Published: 7/31/2025 | Inventor(s): Robert Prins

Keywords(s): adjuvant therapy, Biomarker, Chemotherapy, Clinical Trial, dendritic cell vaccination, Glioblastoma, Glioma, immune response, Immunotherapy, interferon, malignant glioma

Category(s): Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Oncology, Therapeutics > CNS and Neurology

Targeted Epigenetic Editing as Novel Therapy for Malignant Glioma (UCLA Case No. 2023-047)

UCLA Researchers in the Department of Neurology/Neuro-Oncology and the David Geffen School of Medicine have developed methods for the Cas9-CRISPR mediated epigenetic targeting of malignant glioma, and which results in enhanced chemosensitivity to standard chemotherapeutic agents. BACKGROUND: Malignant gliomas are aggressive brain tumors originating...

Published: 7/17/2025 | Inventor(s): Serendipity Rinonos, Albert Lai

Keywords(s): Brain, Cancer, Cancer stem cells, Chemotherapy, Combination therapy, CRISPR, CRISPR-Cas9, Epigenetics, GBM, Glioma

Category(s): Therapeutics > Oncology, Therapeutics > CNS and Neurology