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Search Results - biomarker
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Multi-Particle System for Capture and Detection of Cellular and Molecular Analytes (Case No. 2025-267)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel multi-particle system that selectively confines cells and molecular reactions within cavities formed by interacting particles. Background: Screening and selecting cells with specific, beneficial traits has become a vital process in using cell-derived products...
Published: 7/29/2025
|
Inventor(s):
Dino Di Carlo
,
Alyssa Arnheim
,
Michael Mellody
,
Yuta Nakagawa
,
Lily Shang
Keywords(s):
Assay
,
B Cell
,
barcode
,
Bioassay
,
biological assays
,
Biomarker
,
biomarker
s
,
Biomaterial
,
capping particles
,
CAR-T cell platform
,
CAR-T cell therapy
,
cavities
,
cavity-containing particles
,
Cell and tissue culture
,
cell encapsulation
,
cell engineering
,
cell imaging
,
cell mapping
,
cell sorting
,
cell type identification
,
cell-based therapy
,
centrifugation
,
confinement
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Digital Microfluidics
,
Drug
,
Drug Delivery
,
Drug Discovery
,
drug screening
,
high throughput
,
high throughput assays
,
high throughput testing
,
high-throughput analysis
,
High-Throughput Screening
,
Immunoassay
,
Immunoassay Sense (Molecular Biology)
,
Microfluidics
,
Microfluidics And Mem's
,
Microfluidics Nanosphere
,
microparticles
,
moieties
,
Nanoparticle
,
single cell analysis
,
single cell analysis and testing
,
Single cell data
,
single-cell resolution
,
single-cell trapping
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Cell Counting And Imaging
,
Life Science Research Tools > Lab Equipment
,
Life Science Research Tools > Microscopy And Imaging
,
Life Science Research Tools > Microfluidics And Mems
,
Medical Devices
,
Platforms
Interferon Activation Score Is a
Biomarker
for Immunotherapy in Malignant Glioma Patients (UCLA Case No. 2024-043)
UCLA researchers from the Department of Neurosurgery have characterized immune responses in malignant glioma patients receiving immunotherapy to develop a robust
biomarker
that will allow prediction of clinical outcomes following treatment. BACKGROUND: Malignant gliomas are the most common primary brain tumors in adults. No cures exist and most gliomas...
Published: 7/31/2025
|
Inventor(s):
Robert Prins
Keywords(s):
adjuvant therapy
,
Biomarker
,
Chemotherapy
,
Clinical Trial
,
dendritic cell vaccination
,
Glioblastoma
,
Glioma
,
immune response
,
Immunotherapy
,
interferon
,
malignant glioma
Category(s):
Diagnostic Markers > Immunology
,
Diagnostic Markers > Cancer
,
Therapeutics > Inflammation And Inflammatory Diseases
,
Therapeutics > Oncology
,
Therapeutics > CNS and Neurology
Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of
biomarker
s in bodily fluids....
Published: 2/14/2025
|
Inventor(s):
Aydogan Ozcan
,
Hyouarm Joung
,
Hyun-June Jang
,
Junhong Chen
Keywords(s):
Biomarker
,
biomarker
s
,
Biomaterial
,
Biosensor
,
Computer-Aided Diagnosis
,
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Diagnostic Test
,
Electrical
,
Electrical Engineering
,
electrically-mediated sensing
,
electrochemical sensors
,
enzyme functionalization
,
field-effect transistors (FETs)
,
Medical diagnostics
,
multiplexed analysis
,
Point Of Care
,
point-of-care
,
porous media
,
sample matrix effects
,
transistors
Category(s):
Electrical
,
Electrical > Sensors
,
Medical Devices
,
Medical Devices > Monitoring And Recording Systems
,
Diagnostic Markers
,
Diagnostic Markers > Targets And Assays
,
Platforms
,
Platforms > Diagnostic Platform Technologies
A Uniform AI Framework for Automated Detection of Disease-Related Risk Factors in 3D Medical Imaging Data
Summary: UCLA researchers from the Departments of Anesthesiology & Perioperative Medicine, Ophthalmology, Computational Medicine, and Computer Science have developed a novel uniform framework to diagnose disease-related risk factors in any volumetric medical imaging data. Background: Automated diagnosis of medical imaging is undoubtedly important...
Published: 2/14/2025
|
Inventor(s):
Oren Avram
,
Eran Halperin
,
Berkin Durmus
,
Nadav Rakocz
,
Jeffrey Chiang
,
Srinivas Sadda
Keywords(s):
Advanced Computing / AI
,
AI algorithms
,
Artifical Intelligence (Machine Learning, Data Mining)
,
Artificial Intelligence
,
Biomarker
,
Biomedical Engineering
,
Computer-Aided Design
,
Deep Learning
,
Imaging
,
Magnetic Resonance Imaging
,
Medical Imaging
Category(s):
Software & Algorithms
,
Software & Algorithms > Digital Health
,
Software & Algorithms > Image Processing
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Medical Devices > Medical Imaging
2022-140 Label-Free Virtual HER2 Immunohistochemical Staining of Breast Tissue Using Deep Learning
SUMMARY: UCLA researchers in the Departments of Bioengineering and Electrical and Computer Engineering have developed a deep learning-based algorithm that can detect and quantify the breast cancer marker human epidermal growth factor receptor 2 (HER2) in microscopic images without the need for time-consuming immunohistochemical staining (IHC). BACKGROUND:...
Published: 2/14/2025
|
Inventor(s):
Aydogan Ozcan
,
Yair Rivenson
,
Bijie Bai
,
Hongda Wang
Keywords(s):
Artifical Intelligence (Machine Learning, Data Mining)
,
Biomarker
,
Bladder Cancer
,
Breast Cancer
,
Cancer
,
Cancer Immunotherapy
,
Computer Aided Learning
,
Diagnostic Markers & Platforms
,
Diagnostic Test
,
Fluorescence
,
Fluorescent Labelling
,
HER2/Neu
,
Histology
,
Immune System
,
Immunohistochemistry
,
Life Science Research Tools
,
Machine Learning
,
Optics
,
Research Methods
,
Unsupervised Learning
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Diagnostic Markers
,
Diagnostic Markers > Immunology
,
Medical Devices > Medical Imaging
,
Medical Devices > Medical Imaging > Fluorescence
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Optics & Photonics
2021-100 HIGH-THROUGHPUT DISEASE
BIOMARKER
SCREENING WITH HIGH-TRANSCONDUCTANCE ORGANIC ELECTROCHEMICAL TRANSISTOR ARRAYS
Researchers in UCLA’s Department of Bioengineering have developed a transistor-based biosensor for high-throughput disease
biomarker
screening applications: this minimally invasive sensor features high sensitivity and robustness to competing biomarkers, potentially enabling a next-generation mobile point of care (POC) device.BACKGROUNDMolecular...
Published: 7/17/2025
|
Inventor(s):
Shiming Zhang
,
Ali Khademhosseini
Keywords(s):
Biomarker
Category(s):
Medical Devices