Search Results - ferroptosis

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Methods and Compositions for Treating Melanoma (UCLA Case No. 2021-324)

The Graeber Laboratory at UCLA discovered a novel mechanism for treating melanoma using ferroptosis, a type of programmed cell death, that shows promise against therapy resistance. BACKGROUND: Melanoma is a highly aggressive skin cancer that spreads throughout the body and can be fatal if left untreated. Therapies for melanoma range from immunotherapy...

Published: 7/10/2024 | Inventor(s): Thomas Graeber

Keywords(s): Cancer, ferroptosis, Immunotherapy, MAPK signaling, Melanoma, Oncology, Skin, tumor resistance

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Integrated Molecular and Lipidomic Analysis of Glioma Tumors Identifies Therapeutic Vulnerabilities (UCLA Case No. 2023-210)

UCLA researchers in the Department of Molecular and Medical Pharmacology have uncovered a novel therapeutic target for Glioblastoma leveraging an extensive lipidomic and transcriptomic database. BACKGROUND: Glioblastoma (GBM) is a fast-growing and aggressive brain tumor. The National Brain Tumor Society predicted that over 14,000 people in the United...

Published: 9/25/2024 | Inventor(s): David Nathanson

Keywords(s): Brain cancer, Brain Tumor, cancer target, cell death, ferroptosis, Glioblastoma, lipidomics

Category(s): Therapeutics > Oncology