Search Results - brain+cancer

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Human Glioblastoma Model (UCLA Case No. 2023-273/2024-151)

UCLA researchers in the Department of Biological Chemistry have developed a novel method to study glioblastoma using human brain organoids. BACKGROUND: The National Institutes of Health defines glioblastoma as the most malignant and pervasive subtype of glioma, or glial-based cancer, and report that it is the most common primary brain tumor in adults....

Published: 6/18/2024 | Inventor(s): Aparna Bhaduri

Keywords(s): Brain cancer, Brain organoid, Brain Tumor, Cancer, Glioblastoma, Organoids

Category(s): Therapeutics > CNS and Neurology, Therapeutics > Oncology

Synthetic Lethality of IR with ABBV-155 in Glioblastoma (GBM) (UCLA Case No. 2021-232)

UCLA researchers in the Department of Molecular and Medical Pharmacology have discovered that irradiation therapy can be combined with an antibody drug conjugate to form a novel therapeutic strategy to treat and extend survival of glioblastoma patients. BACKGROUND: Glioblastoma (GBM) is a fast-growing and aggressive brain tumor. The National Brain...

Published: 8/28/2024 | Inventor(s): David Nathanson

Keywords(s): Antibody-Drug Conjugate, Apoptosis, Brain cancer, Cancer, Glioblastoma, irradiation

Category(s): Therapeutics > Oncology

Full Spectrum Computer Vision for Photon Counting CT (Case No. 2024-058)

Summary: Researchers in the Department of Radiological Sciences have developed a machine learning algorithm that processes multispectral photon counting CT data for accurate medical imaging. Background: Photon counting computed tomography (PCCT) is a tremendous engineering advancement, enabling high resolution spectral imaging with myriad applications....

Published: 9/20/2024 | Inventor(s): Matthew Brown, Dieter Enzmann, John Hoffman, Michael Mcnitt-Gray

Keywords(s): AI algorithms, Algorithm, Algorithm Optical Coherence Tomography, algorithmic cancer detection, Artifical Intelligence (Machine Learning, Data Mining), artificial electromagnetic materials, Artificial Intelligence, artificial intelligence augmentation, Artificial Neural Network, Artificial Neural Network Artificial Neuron, artificial-intelligent materials, Big Data, Bladder Cancer, blood cancers, Brain cancer, Breast Cancer, Cancer, cancer antigen, cancer detection, Cancer Immunotherapy, Cancer stem cells, cancer target, Computed tomography, CT, Deep Learning, design software, Digital Pathology, generative artificial intelligence, Genetic Algorithm, Histopathological image analysis, Histopathology, histopathology images, hyperparameter optimization, Image Analysis, Image Processing, lympathic cancers, lymphatic cancer, Medical artificial intelligence (AI), Mesenchymal Stem Cell Derived Cancer Cells, Orthotopic cancer models, Pancreatic cancer, pathology image analysis, Photon counting computed tomography (PCCT), prostate cancer, Radiology, Radiology / Radiomitigation, Software, Software & Algorithms, Software Development Tools, Software-enabled learning

Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Data Analytics

Integrated Molecular and Lipidomic Analysis of Glioma Tumors Identifies Therapeutic Vulnerabilities (UCLA Case No. 2023-210)

UCLA researchers in the Department of Molecular and Medical Pharmacology have uncovered a novel therapeutic target for Glioblastoma leveraging an extensive lipidomic and transcriptomic database. BACKGROUND: Glioblastoma (GBM) is a fast-growing and aggressive brain tumor. The National Brain Tumor Society predicted that over 14,000 people in the United...

Published: 9/25/2024 | Inventor(s): David Nathanson

Keywords(s): Brain cancer, Brain Tumor, cancer target, cell death, ferroptosis, Glioblastoma, lipidomics

Category(s): Therapeutics > Oncology