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Search Results - macular+corneal+dystrophy
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Intrastromal Lamellar Keratoprosthesis (Artificial Cornea) (Case No. 2025-177)
Summary: UCLA researchers in the Department of Ophthalmology have developed an intrastromal artificial cornea implant designed to enhance biointegration and effectively restore vision. Background: Corneal opacities are among the top five causes of blindness worldwide. For patients who are not candidates for conventional corneal transplantation, keratoprosthesis...
Published: 6/16/2025
|
Inventor(s):
Seyed Reza Ghaffari Dehkharghani
,
Anthony Aldave
Keywords(s):
Biologic Medical Product
,
Biomedical Engineering
,
biomedical implantation
,
biomedical sensors
,
diseases of the eye
,
eye disease
,
eye motion
,
eye movement disorders
,
Eye Surgery
,
eye tracking
,
Glaucoma
,
macular corneal dystrophy
,
Macular Degeneration
,
Medical Device
,
Medical Imaging Eyepiece
,
on-eyelid sensor
,
Ophthalmic antibiotics
,
Ophthalmology
,
Other Polymers
,
Polymers
,
Prosthetics
,
Transplant
,
Transplant Rejection
,
transplant surgery
Category(s):
Medical Devices
,
Medical Devices > Surgical Tools
,
Therapeutics > Ophthalmology
CHST6 Mini Gene - CHST6 Expression Construct With Native Promoter (UCLA Case No. 2023-301)
UCLA researchers from the Department of Human Genetics and Department of Ophthalmology have developed a mini gene encoding a protein which is mutated in
macular corneal dystrophy
, leading to a potential gene therapy for this disorder. BACKGROUND: Macular corneal dystrophy (MCD) is a rare genetic disease caused by mutations in the CHST6 gene, which...
Published: 2/14/2025
|
Inventor(s):
Wenlin Zhang
,
Anthony Aldave
Keywords(s):
AAV
,
Adeno-associated viruses (AAV)
,
Gene Editing Systems
,
Gene Therapy
,
genetics
,
keratinocytes
,
macular corneal dystrophy
,
mini gene
,
mutation
,
native promoter
,
Ophthalmology
Category(s):
Therapeutics > Ophthalmology
,
Therapeutics > Gene Therapy And Editing