Search Results - organ+transplant

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A Novel Lymphocyte Stimulation Assay To Quantify Immune Responses (UCLA Case No. 2022-079)

UCLA researchers in the Department of Medicine have developed lymphocyte stimulation assays to evaluate immune responses, supporting various clinical applications such as adjusting immunosuppressant drug levels and advancing COVID-19 vaccine development. The assay systems are reliable, cost-effective, and easy-to-perform, providing accurate assessments...

Published: 2/14/2025 | Inventor(s): Yusaku Shino

Keywords(s): Antibody, biomarkers, cytokines, Immunity (Medical), immunosuppression, Organ Transplant

Category(s): Life Science Research Tools > Antibodies, Therapeutics > Immunology And Immunotherapy

2023-102 A Dynamic Cholesteric Liquid Crystal for Organoid, Spheroid, 3D Cell Aggregate Manufacturing

Summary: UCLA and University of Connecticut researchers have engineered a novel liquid-crystal-based biomaterial with a simple fabrication process for organoid, spheroid and 3D cell aggregate manufacturing that enables rapid cell growth. Background: The current waiting list for people who need a lifesaving organ transplant is over 100,000 cases...

Published: 2/14/2025 | Inventor(s): Paul Weiss, Amir Nasajpour, Ali Tamayol, Mohamadmahdi Samandari

Keywords(s): 3D biofabrication, 3D Printing, Biocompatibility, biocompatible, Biomaterial 3D Printing, biomedical implantation, Cell and tissue culture, Cell Culture, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cholesterol, cholesteryl ester liquid crystals (CLCs), Cultured meat, Electrode 3D Printing, liquid crystal, liquid crystal nanofibers, mesogens, Organ Transplant, organogenesis, scaffolds, self-assemble, Stem Cells / Regenerative Medicine, Tissue Engineering

Category(s): Chemical, Chemical > Polymers, Materials, Materials > Functional Materials, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Medical Devices, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2021-108 PRECISION CONTROL OF TACROLIMUS SERUM LEVEL FOR IMMUNOSUPRESSION OF POST ORGAN TRANSPLANT PATIENTS

Researchers from UCLA’s Department of Mechanical and Aerospace Engineering and the Department of Psychology have created a new approach for the precise management of tacrolimus, improving patient outcomes following organ transplants. This method proved successful in a 60 patient clinical trial compared to controls and can be applied to other similar...

Published: 2/14/2025 | Inventor(s): Chih-Ming Ho, Jeffrey Huy Khong, Megan Lee, Ali Zarrinpar, Un Bi (Viki) Kim

Keywords(s): Organ Transplant

Category(s): Diagnostic Markers > Immunology