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2021-045 Point-of-Care Diagnostic for Detecting the Nucleocapsid Protein of SARS-CoV-2

Summary UCLA researchers in the Department of Bioengineering have developed an easy-to-use diagnostic test for the rapid detection of SARS-CoV-2 in serum. Background: The nucleocapsid protein (N-protein) is a major protein found in coronaviruses like SARS-CoV-2 (COVID-19) which is involved in the packing of RNA within the virus. During the first...

Published: 2/14/2025 | Inventor(s): Daniel Kamei, Daniel Bradbury, Ren Sun, Yushen Du, Benjamin Wu, Jasmine Trinh, Milo Ryan, Cassandra Marie Cantu

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Category(s): Diagnostic Markers, Medical Devices > Monitoring And Recording Systems, Therapeutics > Infectious Diseases > COVID

2020-757 DEVELOPMENT OF A RAPID DETECTION METHOD FOR SARS CORONAVIRUS-2 NUCLEOCAPSID ANTIGENS USING AFFIBODIES DEVELOPED BY MRNA DISPLAY

Intro: UCLA researchers in the Department of Molecular and Medical Pharmacology have discovered high affinity binding affibodies to COVID-19’s nucleocapsid protein that provide the basis for an ELISA-based diagnostic platform. The researchers are currently developing affibody-coated test strips for saliva detection of COVID-19 in high population...

Published: 2/14/2025 | Inventor(s): Ren Sun

Keywords(s):

Category(s): Diagnostic Markers, Therapeutics > Infectious Diseases

2017-515 Genome-Wide Identification of Immune Evasion Functions in a Virus

Case 2017-515UCLA researchers in the Department of Pharmacology have discovered a novel approach toward generating live attenuated influenza vaccines with improved immune response in vivo.BACKGROUNDThe market for human influenza vaccines is expected to reach $4.4 billion by 2021. The majority of these vaccines focus on inactivated or killed viruses,...

Published: 2/14/2025 | Inventor(s): Ren Sun, Yushen Du, Nicholas Wu

Keywords(s): Immunotherapy, Infectious Diseases, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Therapeutics, Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy