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2021-045 Point-of-Care Diagnostic for Detecting the Nucleocapsid Protein of SARS-CoV-2
Summary UCLA researchers in the Department of Bioengineering have developed an easy-to-use diagnostic test for the rapid detection of SARS-CoV-2 in serum. Background: The nucleocapsid protein (N-protein) is a major protein found in coronaviruses like SARS-CoV-2 (COVID-19) which is involved in the packing of RNA within the virus. During the first...
Published: 7/19/2023
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Inventor(s):
Daniel Kamei
,
Daniel Bradbury
,
Ren Sun
,
Yushen Du
,
Benjamin Wu
,
Jasmine Trinh
,
Milo Ryan
,
Cassandra Marie Cantu
Keywords(s):
Category(s):
Diagnostic Markers
,
Medical Devices > Monitoring And Recording Systems
,
Therapeutics > Infectious Diseases > COVID
2020-757 DEVELOPMENT OF A RAPID DETECTION METHOD FOR SARS CORONAVIRUS-2 NUCLEOCAPSID ANTIGENS USING AFFIBODIES DEVELOPED BY MRNA DISPLAY
Intro: UCLA researchers in the Department of Molecular and Medical Pharmacology have discovered high affinity binding affibodies to COVID-19’s nucleocapsid protein that provide the basis for an ELISA-based diagnostic platform. The researchers are currently developing affibody-coated test strips for saliva detection of COVID-19 in high population...
Published: 7/19/2023
|
Inventor(s):
Ren Sun
Keywords(s):
Category(s):
Diagnostic Markers
,
Therapeutics > Infectious Diseases
2019-649 COMPREHENSIVE IDENTIFICATION OF INTERACTING PROTEIN TARGETS USING MRNA DISPLAY OF UNIFORM LIBRARIES
UCLA researchers in the Department of Pharmacology have developed a novel human exon library for mRNA display detection of protein-protein interactions. BACKGROUND:Proteins control all biological functions within a cell. The majority of proteins require interaction with other proteins as partners, to achieve their proper function in cellular machineries....
Published: 7/19/2023
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Inventor(s):
Ren Sun
Keywords(s):
Life Science Research Tools
,
Other
,
Research Methods
,
Targets And Assays
Category(s):
Life Science Research Tools > Research Methods
,
Diagnostic Markers > Targets And Assays
2017-515 Genome-Wide Identification of Immune Evasion Functions in a Virus
Case 2017-515UCLA researchers in the Department of Pharmacology have discovered a novel approach toward generating live attenuated influenza vaccines with improved immune response in vivo.BACKGROUNDThe market for human influenza vaccines is expected to reach $4.4 billion by 2021. The majority of these vaccines focus on inactivated or killed viruses,...
Published: 9/12/2023
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Inventor(s):
Ren Sun
,
Yushen Du
,
Nicholas Wu
Keywords(s):
Immunotherapy
,
Infectious Diseases
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Therapeutics
,
Therapeutics > Infectious Diseases
,
Therapeutics > Immunology And Immunotherapy