Search Results - infectious+diseases

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Use of Dupilumab for Disseminated Fungal Infection (UCLA Case No. 2019-706)
BACKGROUND: Dupilumab, an immunomodulatory drug that blocks IL-4 signaling, is most commonly used to treat moderate-to-severe atopic dermatitis (a form of eczema) and asthma in both adults and adolescents. While fungal infections, such as coccidioidomycosis, can be potentially treated with immunomodulatory drugs, Dupilumab does not currently have...
Published: 5/14/2024   |   Inventor(s): Manish Butte, Maria Garcia-Lloret
Keywords(s): Infectious Diseases, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Infectious Diseases
2012-341 Quantum Dot Enabled Detection of Escherichia Coli using a Cell-Phone
Summary: UCLA researchers in the Department of Electrical Engineering have developed a platform that can detect E. coli using a cell phone. Background: Water and food-associated diseases still pose considerable public health threat even in highly industrialized parts of the world, causing significant amount of hospitalizations and deaths every year....
Published: 7/19/2023   |   Inventor(s): Aydogan Ozcan, Hongying Zhu
Keywords(s): Cell Counting/Imaging, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Image Processing, Infectious Diseases, Photonics
Category(s): Software & Algorithms > Image Processing, Diagnostic Markers, Life Science Research Tools > Cell Counting And Imaging, Platforms > Diagnostic Platform Technologies, Therapeutics > Infectious Diseases, Optics & Photonics
2019-002 Motility-Based Label-Free Detection of Parasites in Bodily Fluids Using Holographic Speckle Analysis and Deep Learning
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed deep learning-based, cost-effective, and portable optical devices that facilitate label-free, high-throughput and sensitive detection of motile parasites. Background: Parasitic infections are a major global public health issue, but current screening...
Published: 10/25/2023   |   Inventor(s): Aydogan Ozcan, Yibo Zhang, Hatice Ceylan Koydemir
Keywords(s): Algorithm, Artificial Intelligence, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Disease, Holography, Imaging, Infection, Infectious Diseases, Infectivity, Monitoring (Medicine), Optics, Software & Algorithms
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Life Science Research Tools, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Infectious Diseases
2021-283 MMHEALTH: MULTIMODAL HEALTH SENSING PLATFORM
SUMMARY: UCLA researchers in the Department of Electrical and Computer Engineering have developed a system that can remotely evaluate patient symptoms and diagnose medical conditions. BACKGROUND: Ensuring that patients are accurately and efficiently diagnosed is of high clinical significance. Current methods require contact-based diagnostic tests...
Published: 11/15/2024   |   Inventor(s): Achuta Kadambi, Laleh Jalilian, Omid Abari, Maxime Cannesson, Ashley Kita, Pradyumna Chari, Adnan Armouti
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Test, Infectious Diseases, Machine Learning, Remote Sensing, Sensors
Category(s): Life Science Research Tools > Research Methods, Life Science Research Tools, Diagnostic Markers, Medical Devices
2020-849-LOW-COST, FAST AND COMPACT EXHALED BREATH CONDENSATE TECHNOLOGY
SUMMARY: UCLA researchers have developed a low-cost method for non-invasive infectious disease testing that can monitor large public spaces for signs of viral outbreaks. BACKGROUND: The ability to test for infectious diseases through non-invasive approaches has become even more prevalent today due to the COVID-19 pandemic. To monitor large populations...
Published: 7/19/2023   |   Inventor(s): Pirouz Kavehpour
Keywords(s): Diagnostic Test, Infection, Infectious Diseases, Infectivity, Medical Device, Viral Load
Category(s): Life Science Research Tools > Other Reagents, Diagnostic Markers, Therapeutics > Infectious Diseases, Therapeutics > Infectious Diseases > COVID
2020-834-DEVICE FOR BLOOD PURIFICATION USING UV LIGHT SOURCE
SUMMARY: UCLA researchers in the Departments of Surgery and Bioengineering have developed a device to sterilize septic blood with ultra violet light. BACKGROUND: The overuse of antibiotics by the agricultural sector has led to an exponential rise in the number of infections that are resistant to traditional antimicrobial agents. Numerous devices...
Published: 7/19/2023   |   Inventor(s): Peyman Benharash, Vishal Dobaria
Keywords(s): Antibacterial, Antiviral Drug, Cardiovascular, Dialysis, Infection, Infectious Diseases, Intravenous Therapy, Medical Device, Sepsis, Ultraviolet
Category(s): Medical Devices, Medical Devices > Surgical Tools
2020-804 COLD PLASMA SANITIZER
UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel sanitizer that is easy to use, safe, portable, and rechargeable, providing an innovative approach for infectious disease control. BACKGROUNDSurface and hand sanitizing is one of the most critical measures to control the spread of infectious diseases. Hands...
Published: 9/5/2023   |   Inventor(s): Richard Wirz, Zhitong Chen
Keywords(s): Infectious Diseases
Category(s): Medical Devices
2019-255 DISCOVERY OF NOVEL ANTI-INFECTIVES FOR GRAM NEGATIVE PATHOGENS
UCLA researchers in the California NanoSystems Institute have discovered novel and potent therapeutic agents against Burkholderia bacteria, E. Coli and pseudomonas bacterial infections through cell-based phenotypic screening that are more effective than existing treatments. BACKGROUND: Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm) cause...
Published: 11/15/2024   |   Inventor(s): Jeffery Miller, Robert Damoiseaux
Keywords(s): Infectious Diseases, Therapeutics & Vaccines
Category(s): Therapeutics > Infectious Diseases
2020-871 SAFE POTENT SINGLE VECTOR PLATFORM VACCINE AGAINST COVID-19
UCLA researchers in the Department of Medicine have utilized a highly attenuated replicating bacterial vector platform to develop a vaccine against SARS-CoV-2 in humans and animals to prevent COVID-19. BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), closely related to SARS-CoV, is an enveloped, single-stranded positive RNA...
Published: 2/29/2024   |   Inventor(s): Marcus Horwitz
Keywords(s): Infectious Diseases, Therapeutics & Vaccines, Vaccines, Viral Delivery Systems
Category(s): Therapeutics > Vaccines, Therapeutics > Infectious Diseases, Therapeutics > Infectious Diseases > COVID
2020-806 SMALL MOLECULE DRUGS FOR CORONAVIRUS INFECTIONS
UCLA researchers in the Department of Molecular and Medical Pharmacology have discovered a group of small molecule compounds that are active against live SARS-CoV-2 at therapeutically relevant concentrations.BACKGROUND: COVID-19 is a global pandemic caused by a newly discovered coronavirus, severe acute respiratory syndrome-related coronavirus (SARS-CoV-2)....
Published: 9/12/2023   |   Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux
Keywords(s): Infectious Diseases, Therapeutics & Vaccines
Category(s): Therapeutics > Infectious Diseases
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