Search Results - therapeutics+%3e+dental

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Zeolite Imidazole Framework-8 (Zif-8)-Based Osteoinductive and Inflammation-Inhibitory Coating for Dental Implants (Case No. 2023-141)

Summary: UCLA researchers from the School of Dentistry have developed zeolitic imidazolate framework-8 (ZIF-8) nanoparticles-based implant coating system for the controlled release of therapeutics. Background: One of the most significant advancements in clinical dentistry over the past four decades is the development of osteointegrated dental implants....

Published: 3/20/2025 | Inventor(s): Alireza Moshaverinia, Weihao Yuan

Keywords(s):

Category(s): Therapeutics, Therapeutics > Dental, Medical Devices, Medical Devices > Coatings, Medical Devices > Surgical Tools, Materials

Oral Health Recommender System (oHRS) For Promoting Oral Self-Care (Case No. 2023-278)

Intro Sentence: UCLA researchers in the department of dentistry developed a system to promote and enhance at-home oral hygiene practices. Background: Dental disease is a chronic illness caused by inadequate and improper oral self-care behaviors. This condition contributes to gum disease, tooth decay, and eventual tooth loss. Traditional oral hygiene...

Published: 2/14/2025 | Inventor(s): Vivek Shetty, Inbal Nahum-Shan, Susan Murphy

Keywords(s): consumer goods and products, Dental, dental care, dental diseases, dental hygiene, digital health system, generative artificial intelligence, health reminder/recommender systems, oral care, tooth decay, toothpaste

Category(s): Therapeutics, Therapeutics > Dental, Software & Algorithms, Software & Algorithms > Digital Health, Medical Devices, Medical Devices > Monitoring And Recording Systems

Method for Diagnosing Dry Mouth Using Biomarkers (UCLA Case No. 2021-252)

SUMMARY: UCLA researchers in the Department of Dentistry have developed a novel and simple method using saliva sampling to detect and monitor xerostomia by testing for the expression of targeted biomarkers. BACKGROUND: Xerostomia, or dry mouth, occurs when salivary glands do not produce enough saliva. Xerostomia ranges in severity from mild discomfort...

Published: 6/26/2025 | Inventor(s): David Wong

Keywords(s):

Category(s): Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics > Dental

2019-698 ENGINEERING AN ANTIMICROBIAL AND OSTEOINDUCTIVE HYDROGEL FOR DENTAL APPLICATIONS

SUMMARY:UCLA researchers in the department of Chemical and Biomolecular Engineering have developed an antimicrobial and osteoinductive hydrogel used for dental implants. BACKGROUND: According to the American Dental Association (ADA), more than 5 million dental implants are performed each year in the United States. The leading cause of failure for these...

Published: 2/14/2025 | Inventor(s): Nasim Annabi

Keywords(s):

Category(s): Therapeutics > Dental

2020-878 Compliant Self-Anchoring Screw

SUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a passively anchoring screw that won’t loosen once it is twisted in place, but can be unscrewed using a screw driver.BACKGROUNDWhile threaded fastener designs allow for easy on/off or replacement, there is always the risk that a screw may come loose...

Published: 2/14/2025 | Inventor(s): Jonathan Hopkins, BAD_EMAIL Hando Kim

Keywords(s):

Category(s): Mechanical, Mechanical > Mechanical Systems, Materials > Construction Materials, Therapeutics > Dental

2020-499 Plasma Source for Oral Health

INTRO SENTENCE:UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a plasma source which overcomes the large size constraints and operating difficulty of existing plasma sources by integrating an ambient air source and portable design that allows for at-home implementation of the technology in fields such as dental...

Published: 2/14/2025 | Inventor(s): Richard Wirz

Keywords(s):

Category(s): Therapeutics > Dental

2020-763 Dental White Spot Treatment

UCLA Researchers in the department of Dentistry have developed a toothpaste formulation for the preventative treatment of dental white spots that otherwise left untreated can lead to cavity formation.BACKGROUND:White spots are a visual indicator of the process of demineralization (early caries) underneath intact dental enamel. Bacteria in the mouth,...

Published: 3/4/2025 | Inventor(s): Alireza Moshaverinia, Sahar Ansari, Benjamin Wu, Mohammad Mahdi Hasani Sadrabadi

Keywords(s): consumer health products, Dental, tooth decay, toothpaste

Category(s): Therapeutics > Dental

2018-149 Salivary extracellular RNA (exRNA) biomarkers for gingivitis

A team from the School of Dentistry and Department of Oral Biology at UCLA has created a non-invasive test to diagnose and track the progression of gingivitis.BACKGROUND:Gingivitis is one of the most prevalent inflammatory diseases in humans and is characterized by irritation and swelling of the gums. If left unchecked, gingivitis can lead to teeth...

Published: 2/14/2025 | Inventor(s): David Wong, Karolina Elzbieta Kaczor-Urbanowicz, Harsh Trivedi, James Masters

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Therapeutics > Dental

2019-876 MAINTAINING FUNCTIONS AND PHENOTYPES OF CONNECTIVE TISSUE THROUGH NPAS2 SUPPRESSION

UCLA researchers in the Departments of Dentistry and Plastic Surgery have developed a novel suppressor of Npas2 for the regeneration of connective tissues.BACKGROUND:Open wounds of the skin and oral cavity are subject to infection and scarring if not properly closed. Patients may experience a variety of social consequences due to unclosed wounds of...

Published: 2/14/2025 | Inventor(s): Ichiro Nishimura, Akishige Hokugo, Hodaka Sasaki, Hiroko Okawa, Lixin Wang

Keywords(s): Dental, Inflammatory Diseases, Therapeutics & Vaccines

Category(s): Therapeutics > Dental, Therapeutics > Inflammation And Inflammatory Diseases

2002-483 Novel Signaling Molecule Utilized by S. Mutans for Biofilm Formation and Quorum Sensing

2002-483 Novel Signaling Molecule Utilized by <i>S. Mutans</i> for Biofilm Formation and Quorum Sensing Background Dental caries is one of the most widespread and costly diseases affecting western and developing countries. Caries arise from acid produced naturally during bacterial metabolism, primarily from oral pathogen Streptococcus mutans....

Published: 2/14/2025 | Inventor(s):

Keywords(s):

Category(s): Therapeutics > Dental

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