Search Results - inflammatory+diseases

11 Results

Sort By:

2013-741 Bioengineered Thymic Aggregates for Implantation

Bioengineered Thymic Aggregates For ImplantationSUMMARYResearchers led by Gay Crooks from the Department of Pathology and Laboratory Medicine at UCLA have bioengineered a thymus implant to treat immune diseases.BACKGROUNDThe thymus plays an important role in the immune cells by producing specialized white blood cells called T cells. Thymus implantation...

Published: 2/14/2025 | Inventor(s): Gay Crooks, Amelie Montel-Hagen, Brile Chung

Keywords(s): Autoimmune, Drug Delivery, Hematology, Inflammatory Diseases, Other Polymers, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Therapeutics > Autoimmune, Therapeutics > Hematology, Platforms > Drug Delivery > Other Polymers, Therapeutics > Immunology And Immunotherapy

2019-876 MAINTAINING FUNCTIONS AND PHENOTYPES OF CONNECTIVE TISSUE THROUGH NPAS2 SUPPRESSION

UCLA researchers in the Departments of Dentistry and Plastic Surgery have developed a novel suppressor of Npas2 for the regeneration of connective tissues.BACKGROUND:Open wounds of the skin and oral cavity are subject to infection and scarring if not properly closed. Patients may experience a variety of social consequences due to unclosed wounds of...

Published: 7/17/2025 | Inventor(s): Ichiro Nishimura, Akishige Hokugo, Hodaka Sasaki, Hiroko Okawa, Lixin Wang

Keywords(s): Dental, Inflammatory Diseases, Therapeutics & Vaccines

Category(s): Therapeutics > Dental, Therapeutics > Inflammation And Inflammatory Diseases

Early Prediction of Progression in Idiopathic Pulmonary Fibrosis Using a Single Time Point HRCT Scan (Case No. 2019-731)

Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel single time point high-resolution computed tomography (HRCT) scan method for the early prediction of idiopathic pulmonary fibrosis disease progression. Background: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease that results in scarring of the lungs...

Published: 7/17/2025 | Inventor(s): Grace Hyun Kim, Jonathan Goldin

Keywords(s): CT, Diagnostic Markers & Platforms, Inflammatory Diseases, Life Science Research Tools, Medical Imaging, Microscopy And Imaging

Category(s): Life Science Research Tools > Microscopy And Imaging, Medical Devices > Medical Imaging > CT, Therapeutics > Inflammation And Inflammatory Diseases

2019-468 PERIODONTAL MICROPATCH AND USES THEREOF

INTRODUCTION:UCLA researchers in the Departments of Bioengineering and Dentistry have developed a patch-based drug delivery system for dental applications.BACKGROUND:Periodontitis is a chronic inflammatory disease that affects tissues surrounding the teeth, and it is estimated that 50% of the U.S. population suffers from some type of periodontal disease....

Published: 7/17/2025 | Inventor(s):

Keywords(s): Dental, Drug Delivery, Inflammatory Diseases, Medical Devices and Materials, Other Polymers

Category(s): Platforms > Drug Delivery > Other Polymers

2016-518: Inhibition of Protein Tyrosine Phosphatase-Sigma for Hematopoietic Regeneration

Inhibition Of Protein Tyrosine Phosphatase - Sigma For Hematopoietic RegenerationSUMMARYUCLA Researchers have identified a novel pharmacological target for hematopoietic stem cell regeneration. They have developed small molecule inhibitors against the target and shown that the inhibitors cause rapid stem cell regeneration.BACKGROUNDDepletion of white...

Published: 7/17/2025 | Inventor(s): John Chute, Michael Jung, Emelyne Diers

Keywords(s): Autoimmune, Hematology, Inflammatory Diseases, iPS/stem cells, Oncology

Category(s): Therapeutics > Autoimmune, Therapeutics > Oncology, Therapeutics > Hematology, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

2018-388 METABOLIC REQUIREMENTS FOR ALTERNATIVE MACROPHAGE ACTIVATION

Metabolic Requirements for Alternative Macrophage ActivationSUMMARYUCLA researchers in the Department of Molecular and Medical Pharmacology have discovered that Coenzyme A is a targetable requirement for anti-inflammatory macrophage differentiation.BACKGROUNDA dysregulated immune response is a hallmark of many disease phenotypes. For instance, cancer...

Published: 7/17/2025 | Inventor(s): Steven Bensinger, Ajit Divakaruni, Anne Murphy, Wei Yuan Hsieh

Keywords(s): Autoimmune, Drug Delivery, Infectious Diseases, Inflammatory Diseases, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Therapeutics, Therapeutics > Autoimmune, Therapeutics > Infectious Diseases, Therapeutics > Inflammation And Inflammatory Diseases

2018-159 Therapeutic Approach to Prevent or Alleviate Drug-, Noise- and Age-Related Hearing Loss

Therapeutic Approach To Prevent Or Alleviate Drug-, Noise- And Age-Related Hearing LossSUMMARYUCLA researchers in the Department of Head and Neck Surgery have developed a novel therapeutic approach to treating hearing loss using inflammation-resolving molecules.BACKGROUNDMore than 350 million people worldwide exhibit some degree of hearing loss, with...

Published: 7/17/2025 | Inventor(s): Jennifer Long, Federico Kalinec

Keywords(s): Drug Delivery, Inflammatory Diseases, Nanoparticles, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Therapeutics, Therapeutics > Inflammation And Inflammatory Diseases, Platforms > Drug Delivery > Nanoparticles

A Novel Method To Enhance Tg6f Amelioration Of Dyslipidemia

SummaryUCLA researchers in the Department of Medicine have developed a novel protocol that enhances the effects of Tg6F in treating dyslipidemia.BackgroundDyslipidemia is characterized as having abnormal levels of cholesterol or triglycerides in the blood, resulting in an imbalance of circulating lipids. Patients with dyslipidemia tend to have a higher...

Published: 7/17/2025 | Inventor(s): Alan Fogelman, Srinivasa Reddy, Mohamad Navab

Keywords(s): Cardiovascular, Inflammatory Diseases, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Inflammation And Inflammatory Diseases

Systems And Methods For Therapeutic Agent Delivery

SummaryUCLA researchers at the Department of Physics have developed a system that is capable of delivering a therapeutic agent to a specifically targeted tissue using ultrasound.BackgroundSoft tissue infections are a major global health issue. About 325,000 new cases are diagnosed each year. When an inadequate concentration of antibiotic is used to...

Published: 7/17/2025 | Inventor(s): Seth Putterman, Barry Silberg

Keywords(s): Drug Delivery, Infectious Diseases, Inflammatory Diseases, Medical Devices and Materials, Ultrasound

Category(s): Medical Devices, Platforms > Drug Delivery, Medical Devices > Medical Imaging > Ultrasound, Therapeutics > Infectious Diseases, Therapeutics > Inflammation And Inflammatory Diseases

2011-788 Use of ApoA-1 to Treat and Prevent Pro-Inflammatory Conditions

UCLA researchers in the Department of Obstetrics and Gynecology have discovered that ApoA-I can be used to treat and prevent pro-inflammatory skin conditions.BACKGROUNDInflammation is a standard immune signaling process that is strongly associated with stress and is connected to various diseases. Inflammation is activated to fight infection or invasion...

Published: 7/17/2025 | Inventor(s): Srinivasa Reddy, Robin Farias-Eisner

Keywords(s): Autoimmune, Dermatology, Inflammatory Diseases, Oncology, Oncology (Small Molecules, Peptides and Antibodies), Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Autoimmune, Therapeutics > Dermatology, Therapeutics > Oncology, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Oncology > Oncology (Small Molecules)

1 2