Search Results - therapeutics+%3e+respiratory+and+pulmonary

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Combination Cancer Therapy Methods and Agents (UCLA Case No. 2024-084)

UCLA researchers from the Department of Medicine, Pathology, & Laboratory Medicine and Molecular & Medical Pharmacology have identified a novel cell-based therapy that leads to enhanced immunotherapy efficacy and overcomes treatment resistance to immune checkpoint blockade in non-small cell lung cancer. BACKGROUND: Non-small cell lung cancer...

Published: 11/4/2024 | Inventor(s): Bin Liu, Steven Dubinett

Keywords(s): anti-tumor immunity, cell-based therapy, Immune checkpoint blockade, Immunotherapy, non-small cell lung cancer, treatment resistance, Tumor microenvironment, Vaccines

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Respiratory And Pulmonary

Summary: UCLA researchers have developed a novel method to characterize lung tissue biomechanics and applied it to the creation of a computational model to improve understanding and visualization of lung diseases. Background: Chronic lower respiratory disease (ex. COPD) was the sixth leading cause of death in the United States in 2021, taking nearly...

Published: 7/25/2024 | Inventor(s): Anand Santhanam, Brad Stiehl

Keywords(s): Biomechanics, cardiopulmonary illness, Respiratory & Pulmonary, Simulation & Modeling

Category(s): Software & Algorithms > Statistical Models, Software & Algorithms > Digital Health, Therapeutics > Respiratory And Pulmonary

Summary: UCLA researchers have developed a novel method to characterize lung tissue biomechanics and applied it to the creation of a computational model with which to guide lung elastography. Background: Lung cancer is the leading cause of death from cancer in people in the US. With an increasing focus on improving the patient’s quality of...

Published: 3/27/2024 | Inventor(s): Anand Santhanam, Brad Stiehl

Keywords(s): Biomechanics, cardiopulmonary illness, Respiratory & Pulmonary, Simulation & Modeling

Category(s): Software & Algorithms > Statistical Models, Software & Algorithms > Digital Health, Therapeutics > Respiratory And Pulmonary

Stabilized Right Atrial to Pulmonary Artery Cannula for Extracorporeal Life Support (Case No. 2023-231)

Summary: UCLA researchers in the department of surgery developed a right atrial to pulmonary canula for extracorporeal life support. Background: Extracorporeal life support (ECLS) is a last-resort medical intervention designed to support patients with severe cardiac or pulmonary failure. This technology involves the diversion of blood flow to an...

Published: 10/25/2024 | Inventor(s): Peyman Benharash, Joseph Hadaya, Yas Sanaiha, Ali Nsair

Keywords(s): Advanced Life Support, blood flow management, cannula, Cardiac failure, cardiopulmonary illness, cardiovascular therapeutic solution, extracorporeal life support (ECLS), heart support, Intensive care unit (ICU), pulmonary failure, respiratory failure, right atrial to pulmonary canula

Category(s): Medical Devices, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Respiratory And Pulmonary

2019-044: Sodium-Dependent Glucose Transporter 2 as a Diagnostic and Therapeutic Target for Early-Stage Cancer

SUMMARY: UCLA researchers in the Department of Medicine have developed a clinical screening method for early-stage lung cancer utilizing a newly discovered biomarker and subsequently shown that inhibitors of this biomarker result in cancer interception. BACKGROUND: The National Cancer Institute reports that lung cancer accounts for 28% of all...

Published: 9/5/2023 | Inventor(s): Claudio Scafoglio, Steven Dubinett

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary

2021-092 FLOW REGULATION MECHANISM FOR COMPARTMENTALIZED LUNG VENTILATION

SUMMARY: UCLA researchers in the Department of Pulmonary and Clinical Care have developed a device capable of analyzing individual lungs in real-time to improve the quality of care for mechanically ventilated patients. BACKGROUND: Ventilators aid patients that have difficulty breathing by pressing positive air pressure into their lungs. Mechanical...

Published: 7/19/2023 | Inventor(s):

Keywords(s): Angiogenesis Acute Lung Injury, Diagnostic Test, Drug Delivery, Instrumentation, Lung, Lung Pulmonology, Medical Device, Medical Imaging, Monitoring And Recording Systems, Respiratory & Pulmonary, Sensors, Software

Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Therapeutics > Infectious Diseases > COVID, Therapeutics > Respiratory And Pulmonary, Software & Algorithms > Programs

2020-163 POSITRON EMISSION TOMOGRAPHY GUIDED DELIVERY OF MITOCHONDRIAL COMPLEX I INHIBITORS

UCLA researchers in the David Geffen School of Medicine Division of Pulmonary and Critical Care Medicine have developed a novel use of the positron emission tomography (PET) tracer [18F]FBnTP to guide the delivery of mitochondrial complex I inhibitors for the treatment of lung cancers.BACKGROUND: The mitochondria are essential regulators of cellular...

Published: 7/19/2023 | Inventor(s): David Shackelford, Saman Sadeghi, Milica Momcilovic

Keywords(s): Diagnostic Markers & Platforms, Imaging, Medical Imaging, PET, Respiratory & Pulmonary

Category(s): Medical Devices > Medical Imaging > PET, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary

2011-739 LIS-LUNG ISOLATION SYSTEM

Lung Isolation and One-Lung Ventilation SystemSUMMARYDr. Nir Hoftman in the Department of Anesthesiology has developed a novel one-lung ventilation system that is deployed through a standard endotracheal breathing tube and achieves reliable, switchable isolation of either lung, along with integrated imaging ability.BACKGROUNDSurgeries of the lung and...

Published: 7/19/2023 | Inventor(s): Nir Hoftman, Aman Mahajan

Keywords(s):

Category(s): Medical Devices, Medical Devices > Surgical Tools, Therapeutics > Respiratory And Pulmonary

2016-049 Automated Optical Chest Tube Air Leak Detection System

Automated Optical Chest Tube Air Leak Detection SystemSUMMARYUCLA researchers in the Department of Surgery have developed an air leak detection system for use in patients requiring chest tube placement.BACKGROUNDThe standard “state of the art” in the vast majority of medical situations requiring chest tube placement is for the tube to be...

Published: 7/19/2023 | Inventor(s): Peyman Benharash, Robert Cameron, Allen Zhu

Keywords(s): Medical Devices and Materials, Respiratory & Pulmonary

Category(s): Medical Devices, Therapeutics > Respiratory And Pulmonary