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2016-404 NEW METHOD TO INCREASE THE LIGATION RATE OF REACTIONS CATALYZED BY THE S. AUREUS SORTASE A ENZYME

New Method to Increase the Rate of Protein Ligation Catalyzed by the S. Aureus Sortase A EnzymeSUMMARYUCLA researchers in the Department of Chemistry and Biochemistry have developed a new method to increase the rate of ligation catalyzed by the S. aureus Sortase A enzymeBACKGROUNDThe sortase A (SrtA) enzyme from Staphylococcus aureus is widely used...

Published: 9/12/2023 | Inventor(s): Robert Clubb, Brendan Amer

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Category(s): Life Science Research Tools

2018-463 REAGENT TO LABEL PROTEINS VIA LYSINE ISOPEPTIDE BONDS

Reagent to Label Proteins via Lysine Isopeptide BondsSUMMARYResearchers in the UCLA Department of Chemistry and Biochemistry and the University of Texas-Medical Center, Houston Department of Microbiology and Molecular Genetics have modified the Corynebacterium diphtheriae (C. diphtheriae) sortase enzyme so that it can be used as a bioconjugation reagent...

Published: 9/12/2023 | Inventor(s): Robert Clubb, Brendan Amer, Hung Ton-That, Chungyu Chang, Janine Fu, Scott Mcconnell

Keywords(s): Antibodies, Antibody Delivery Platforms, Diagnostic Markers & Platforms, Drug Delivery, Infectious Diseases, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Diagnostic Markers, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Therapeutics, Therapeutics > Infectious Diseases