Search Results - kanagasabai+vadivel

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2018-028 PATHWAY-DEPENDENT INHIBITION OF PROTEOPATHIC SEED TRANSMISSION

Pathway-Dependent Inhibition Of Proteopathic Seed TransmissionSUMMARYUCLA researchers in the Department of Neurology have developed a novel approach to stop the propagation of proteopathic diseases, which could be applied to wide range of neurodegenerative disorders including Alzheimer’s disease and Parkinson’s disease.BACKGROUNDProteopathy...

Published: 7/19/2023 | Inventor(s): Neil Garg, Varghese John, Kanagasabai Vadivel, Barbara Jagodzinska, Tina Bilousova

Keywords(s): Cns, Life Science Research Tools, Targets And Assays, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Diagnostic Markers > Targets And Assays, Therapeutics, Therapeutics > CNS and Neurology

2017-772 ALLOSTERIC BACE INHIBITORS FOR TREATMENT OF ALZHEIMER’S DISEASE

Allosteric BACE Inhibitors For Treatment Of Alzheimer’s DiseaseSUMMARYUCLA researchers from the Department of Neurology have discovered a new class of drug candidates for Alzheimer’s disease. These small molecule compounds can specifically inhibit target enzymes to prevent target protein cleavage through an allosteric mechanism, preventing...

Published: 9/5/2023 | Inventor(s): Varghese John, Barbara Jagodzinska, Patricia Spilman, Jesus Campagna, Kanagasabai Vadivel, Michael Jung

Keywords(s): Cns, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > CNS and Neurology