Search Results - mohammad+hasani-sadrabadi

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Biomaterial-Based Vaccine Booster to Enhance Long-Term Immunity (UCLA Case No. 2021-170)

UCLA researchers have developed injectable, cell-free, and biomaterial-based microparticles that can engage with tissue resident immune cells and enhance long-term immunity. It is the first biomaterial-based, targeted approach to induce T memory stem cells (TMSCs) in vivo. The approach was demonstrated for SARS-CoV-2 but can be used for any vaccine....

Published: 2/26/2024 | Inventor(s): Mohammad Hasani-Sadrabadi, Song Li, Manish Butte

Keywords(s): aAPCs, Aging, artificial presenting cells, cytokines, elderly, immunosenescence, microparticles, platform technology, SARS-CoV-2, T memory stem cells, TMSCs, Vaccines

Category(s): Therapeutics > Infectious Diseases, Therapeutics > Oncology

Immunoactive Microparticles and Uses Thereof (UCLA Case No. 2020-200)

SUMMARY: UCLA Researchers from the division of Immunology in the David Geffen School of Medicine have developed an improved method of stimulating anti-tumor T-cells for use in cancer immunotherapy. BACKGROUND: Cancer immunotherapy, a therapeutic strategy whereby a patient’s own immune system is reequipped to attack cancer cells, promises more...

Published: 4/9/2024 | Inventor(s): Manish Butte, Mohammad Hasani-Sadrabadi, Fatemeh Sadat Majedi, Song Li

Keywords(s):

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy, Materials > Nanotechnology

Novel Vaginal Drug Delivery Device (UCLA Case No. 2020-444)

Summary: UCLA researchers in the Departments of Biomedical Engineering and Medicine have developed vaginal drug delivery devices for the administration of contraceptives and antibiotics. Background: Globally, 1.9 billion women of reproductive age (15-49 years) use contraceptives. An additional 190 million women would use phrophylactics/contraceptives...

Published: 10/17/2024 | Inventor(s): Leena Nathan, Song Li, Tamara Grisales, Mohammad Hasani-Sadrabadi

Keywords(s):

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Platforms > Drug Delivery > Other Polymers

2020-421 EXTRACELLULAR VESICLES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS FOR IMMUNOMODULATION

UCLA researchers in the Department of Bioengineering have developed a method to boost extracellular vesicles' (EVs) production and potency, potentially allowing large-scale clinical-grade EV manufacture for immunomodulatory therapeutics. BACKGROUNDExtracellular vesicles (EVs) are one of the most important mediators of cell-to-cell communication. EVs...

Published: 7/19/2023 | Inventor(s): Jana Zarubova, Mohammad Hasani-Sadrabadi, Song Li

Keywords(s): Immunology, Therapeutics & Vaccines, Transplant Rejection

Category(s): Life Science Research Tools > Research Methods, Therapeutics > Agtech And Animal Health, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells

Biomimetic Artificial Periodontal Membranes and Method of Fabricating the Same (Case No. 2018-369)

Summary: UCLA researchers in the Departments of Dentistry and Chemistry have developed a novel biomimetic and degradable periodontal polymer membrane for use in guided tissue regeneration. Background: Periodontitis is a chronic destructive inflammatory disease of tooth-supporting tissue that affects more than 64 million American adults, with inadequate...

Published: 8/8/2023 | Inventor(s): Alireza Moshaverinia, Paul Weiss, Mohammad Hasani-Sadrabadi

Keywords(s): Dental, Medical Devices and Materials

Category(s): Medical Devices, Therapeutics > Dental

Dental Adhesive Hydrogels and Uses Thereof (Case No. 2017-897)

Summary: Researchers at the UCLA School of Dentistry and the Department of Chemistry & Biochemistry have developed novel biodegradable, photocurable, and non-toxic hydrogel-based adhesives, which can be used for periodontal tissue regeneration and personalized precision oral care. Background: In the field of tissue engineering, biomaterials are...

Published: 4/12/2024 | Inventor(s): Alireza Moshaverinia, Paul Weiss, Mohammad Hasani-Sadrabadi

Keywords(s): Dental, Medical Devices and Materials

Category(s): Medical Devices, Therapeutics > Dental

Bioactive Adhesive Dental Restorative Cement (Case No. 2017-979)

Bioactive Adhesive Dental Restorative CementSUMMARYResearchers led by Alireza Moshaverinia from the School of Dentistry at UCLA have developed a novel restorative dental cement that promotes remineralization of damaged teeth.BACKGROUNDDental restorative materials are used to fill in cavities or to replace lost tooth structure due to trauma (i.e. a chipped...

Published: 4/24/2024 | Inventor(s): Alireza Moshaverinia, Mohammad Hasani-Sadrabadi

Keywords(s): Dental, Medical Devices and Materials, Therapeutics & Vaccines

Category(s): Medical Devices, Therapeutics, Therapeutics > Dental