Search Results - pei+yu+chiou

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High-Throughput Cargo Delivery Into Live Cells Using Photothermal Platforms (Case No. 2013-158)

Summary: UCLA researchers in the Department of Mechanical Engineering have developed a photothermal platform for precisely opening a cell membrane to deliver cargo into cells. Title: High-Throughput Cargo Delivery Into Live Cells Using Photothermal Platforms Background: Transferring cargo like proteins, nucleotides and particles into cells is valuable...

Published: 10/24/2024 | Inventor(s): Pei Yu Chiou, Michael Teitell, Ting Hsiang Wu, Yi-Chien Wu

Keywords(s): cell engineering, cellular, delivery system, Gene delivery, Laser, Microbiology, Micropump

Category(s): Electrical > Mems, Life Science Research Tools > Microfluidics And Mems

Label-Free Optical Mapping for Large-Area Biomechanical Dynamics of Multicellular Systems (Case No. 2023-290)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel label-free optical mapping method for profiling real-time biomechanical dynamics over larger areas with high spatiotemporal resolution. Background: Mapping biomechanical dynamics often involves the use of various advanced technologies to measure...

Published: 6/27/2024 | Inventor(s): Pei Yu Chiou, Yen-Ju Lin

Keywords(s): bioimaging, Biomechanics, cell imaging, Confocal Microscopy, dye, Fluorescence Microscope, labeling, Microscopy, Microscopy And Imaging, resolution, traction force microscopy

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Cell Counting And Imaging, Medical Devices, Medical Devices > Medical Imaging, Platforms, Platforms > Diagnostic Platform Technologies

2020-908 LASER ACTUATED SUPERCRITICAL INJECTOR (LASI)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering developed a platform that applies high-speed fluidic jet injection of biomolecules into biological samples with the use of laser actuated supercritical injector (LASI). Background: Intracellular delivery of various biomolecules has been of great importance in biomedical...

Published: 7/19/2023 | Inventor(s): Pei Yu Chiou

Keywords(s):

Category(s): Life Science Research Tools > Microfluidics And Mems, Platforms > Drug Delivery, Optics & Photonics, Materials > Nanotechnology

Mechanisms and Devices Enabling Arbitrarily Shaped, Deep-Subwavelength, Acoustic Patterning

UC Case No. 2019-852SUMMARY:UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a Compliant Membrane Acoustic Patterning (CAMP) technology capable of patterning cells in an arbitrary pattern at a high resolution over a large area. BACKGROUND:Acoustic force has been investigated as a noninvasive, label-free, and...

Published: 7/19/2023 | Inventor(s): Pei Yu Chiou, Kuan-Wen Tung, Benjamin Wu

Keywords(s): Cell Counting/Imaging, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Life Science Research Tools, Medical Devices and Materials, Microfluidics And Mem's, Monitoring And Recording Systems

Category(s): Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies

Liquid Metal Enabled Multifunctional Neural Probes with Ultra-Large Tunable Stiffness

UC Case No. 2019-327SUMMARY: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel multifunctional neural probe with ultra-large tunable stiffness for electrochemical sensing and chemical delivery in the brain. BACKGROUND: Measuring brain activity has enormous applications including disease diagnosis...

Published: 7/19/2023 | Inventor(s): Pei Yu Chiou, Ximiao Wen, Nigel Maidment, Brian Bo Wang

Keywords(s): Medical Devices and Materials

Category(s): Medical Devices > Monitoring And Recording Systems

2016-044 Plasmonic Nanoparticle Embedded PDMS Micropillar Array and Fabrication Approaches for Large Area Cell Force Sensing

Plasmonic Nanoparticle Embedded PDMS Micropillar Array and Fabrication Approaches for Large Area Cell Force SensingSUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel cell force sensor platform with high accuracy over large areas.BACKGROUNDMicrofabricated elastic pillar substrates with various geometries...

Published: 7/19/2023 | Inventor(s): Fan Xiao, Pei Yu Chiou

Keywords(s): Electronics & Semiconductors, Life Science Research Tools, Microscopy And Imaging, Photonics

Category(s): Electrical > Electronics & Semiconductors, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Materials > Fabrication Technologies, Optics & Photonics

Single-Pixel Optical Technologies For Instantly Quantifying Multicellular Response Profiles

UC Case No. 2017-999SUMMARY:UCLA researchers in the Department of Mechanical & Aerospace Engineering and the Department of Pathology & Lab Medicine have proposed a new platform technology to actuate and sense force propagation in real-time for large sheets of cells.BACKGROUND:In multicellular organisms, chemical gradients, electrical impulses,...

Published: 7/19/2023 | Inventor(s): Michael Teitell, Pei Yu Chiou, Thang Nguyen, Xing Haw Marvin Tan, Xiongfeng Zhu

Keywords(s): Cell Counting/Imaging, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Medical Imaging, Microscopy And Imaging

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Diagnostic Markers, Life Science Research Tools > Cell Counting And Imaging, Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies

Self-Locking Optoelectronic Tweezer and its Fabrication

UC Case No. 2015-107SUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel self-locking optoelectronic tweezer (SLOT) for single cell manipulation in conductive buffer over large areas.BACKGROUNDOptoelectronic tweezers (OETs) use projected optical images to trap and transport tiny particles in parallel...

Published: 7/19/2023 | Inventor(s): Pei Yu Chiou, Chi On Chui, Yufei Mao, Yajia Yang

Keywords(s): Electronics & Semiconductors, Optics, Photonics

Category(s): Electrical > Electronics & Semiconductors, Materials > Fabrication Technologies, Optics & Photonics

2016-485 TUNABLE, SHEATHLESS, AND THREE DIMENSIONAL SINGLE-STREAM CELL FOCUSING IN HIGH SPEED FLOWS

Tunable, Sheathless, and Three Dimensional Single-Stream Cell Focusing in High Speed FlowsTech ID: 30473 / UC Case 2016-485-0SUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a tunable, sheathless, and three dimensional single-stream cell focusing in high speed flows. This new mechanism can be used for...

Published: 7/19/2023 | Inventor(s): Pei Yu Chiou, Yu Chun Kung

Keywords(s): Cell Counting/Imaging, Life Science Research Tools, Microfluidics And Mem's

Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microfluidics And Mems