Search Results - tumor

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Inhibition of BMI1 Eliminated Cancer Stem Cells and Activates Antitumor Immunity (UCLA Case No. 2020-858)

UCLA researchers in the Department of Dentistry discovered that targeting BMI1in head and neck squamous cell carcinoma (HNSCC) may be a viable immune checkpoint to inhibit metastatic tumor growth, and prevent tumor relapse through activation of cell-intrinsic immunity and purging cancer stem cells (CSCs). BACKGROUND: Cancer stem cells are cancer...

Published: 7/17/2025 | Inventor(s): Cun Yu Wang, Jia Lingfei

Keywords(s): Cancer stem cells, Epigenetics, Immunooncology, Oncology Immunotherapy, Tumor

Category(s): Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Gene Therapy And Editing

Novel Method to Group Pixels for Medical Imaging (UCLA Case No. 2022-290)

Summary: UCLA researchers in the Department of Radiological Sciences have developed a new computational pipeline for identifying lesions in MRI data. Background: Prostate cancer is one of the most common cancer types with 12.6% of men diagnosed within their lifetime. Prostate cancer ranks as the 2nd leading cause of cancer-related deaths in the...

Published: 2/14/2025 | Inventor(s): Ashley Yeager

Keywords(s): AI algorithms, Algorithm, algorithmic cancer detection, Cancer, cancer detection, DICOM, multiparametric MRI (mpMRI), prostate cancer, Radiology, Software & Algorithms, Tumor, Tumor Marker

Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Digital Health

2023-009: Repurposing Native Cytokine Receptor Signaling for Adoptive T Cell Therapy of Cancer

SUMMARY: UCLA researchers in the Department of Radiation Oncology at the School of Medicine have identified a cytokine receptor endowing adoptively transferred T cells with new functions that enhance the potency of adoptively transferred T cells for the treatment of solid tumors, namely by restoring their functionality in the absence of conditioning...

Published: 10/8/2025 | Inventor(s): Anusha Kalbasi

Keywords(s): Cancer, Immunotherapy, Tumor

Category(s): Life Science Research Tools, Therapeutics

2021-344 Biopsy-Free In Vivo Virtual Histology of Skin Using Deep Learning

Summary: UCLA researchers in the Departments of Electrical and Computer Engineering & Bioengineering have developed a non-invasive, biopsy-free technique for in vivo virtual histology of skin cancer using deep learning. Background: Tissue biopsies have often been used to diagnose skin cancers in patients. These procedures are generally cumbersome...

Published: 7/17/2025 | Inventor(s): Aydogan Ozcan, Jingxi Li, Yair Rivenson, Xiaoran Zhang, Philip Scumpia, Jason Garfinkel, Gennady Rubinstein

Keywords(s): Artificial Intelligence, Biopsy, Cancer, Confocal Microscopy, Diagnostic Test, Histology, Image Resolution, Invasiveness Of Surgical Procedures, Melanoma, Optics, Skin, Software, Tissue (Biology), Tumor

Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Electrical > Imaging, Medical Devices > Medical Imaging, Optics & Photonics