Search Results - vaithilingaraja+arumugaswami

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Antiviral Compounds Inhibiting Mpox Virus, and Methods and Mpox Treatment Thereof (UCLA Case No. 2025-037)

UCLA researchers from the Department of Molecular and Medical Pharmacology have identified potent drug candidates inhibiting monkeypox virus, which may be used as therapies to prevent or treat viral infections. BACKGROUND: Monkeypox (mpox) is a viral infection related to smallpox that manifests as a rash, lesions, swollen lymph nodes, and flu-like...

Published: 10/22/2025 | Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux

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Category(s): Therapeutics > Infectious Diseases

Antiviral Compounds Inhibiting Zika Virus (ZIKV), and Methods and Zika Treatment Thereof (UCLA Case No. 2025-241)

UCLA researchers from the Molecular and Medical Pharmacology Department and CNSI have identified antiviral compounds that effectively inhibit Zika virus infection and cytopathic effects, potentially leading to improved therapeutics and treatment outcomes. BACKGROUND: Zika virus (ZIKV), a flavivirus now endemic to several regions globally, can cause...

Published: 10/3/2025 | Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux

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Category(s): Life Science Research Tools > Screening Libraries, Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Therapeutics > Infectious Diseases, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Platforms > Diagnostic Platform Technologies

Structure-Based Design of Antisense Oligonucleotide Drugs (UCLA Case No. 2020-916)

UCLA researchers led by Professor Feng Guo have developed a next-generation platform for designing antisense oligonucleotide (ASO) therapeutics using RNA structure as a blueprint, achieving enhanced specificity, efficacy, and versatility for the treatment of a wide spectrum of genetic and infectious diseases. INNOVATION: UCLA researchers in the Department...

Published: 9/12/2025 | Inventor(s): Feng Guo, Vaithilingaraja Arumugaswami

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Category(s): Platforms, Therapeutics > Infectious Diseases, Therapeutics > Genetic Diseases

2020-919-4 COVID 19 CELL MODEL SYSTEMS AND ANTIVIRAL AGENTS

SUMMARY: Researchers from UCLA’s Department of Molecular and Medical Pharmacology in collaboration with external collaborators have developed a platform for complex testing of antiviral agents in multiple cell models. Currently this technology is optimized for Coronavirus-type strains, but the system can easily be adapted to other viral pathogens....

Published: 7/3/2025 | Inventor(s): Vaithilingaraja Arumugaswami

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Category(s): Life Science Research Tools > Research Methods, Life Science Research Tools, Diagnostic Markers > Targets And Assays, Therapeutics > Infectious Diseases

2019-880 ZIKA VIRUS-BASED ONCOLYTIC THERAPY FOR BRAIN CANCER

UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a novel zika virus-based oncolytic therapy to treat brain cancer.BACKGROUND: Glioma is a type of brain tumor that accounts for 80% of all primary malignant brain tumors. Standard therapy for high-grade glioma requires a combination of surgical resection, radiation...

Published: 7/17/2025 | Inventor(s): Vaithilingaraja Arumugaswami, David Nathanson

Keywords(s): Cns, Drug Delivery, Gene Editing Systems, Gene Therapy, Immunology, Immunotherapy, Oncology, Oncology Immunotherapy, Plasmids / Vectors, Therapeutics & Vaccines, Viral Delivery Systems

Category(s): Diagnostic Markers > Immunology, Therapeutics > CNS and Neurology, Therapeutics > Vaccines, Therapeutics > Oncology, Therapeutics > Gene Therapy And Editing, Therapeutics > Oncology > Oncology Immunotherapy

Multilayer Batch Microfabricated Magnetic Shielding

UCLA Case No. 2018-014 SUMMARYUCLA researchers in the Department of Electrical Engineering have developed a novel batch microfabrication technique for microscale shielding layers, simultaneously pushing the limits of minimum size, maximum shielding factor, flexibility, and cost.BACKGROUNDCompact electromagnetic shielding paves the way for a new generation...

Published: 7/17/2025 | Inventor(s): Robert Candler, Jimmy Chen-Yen Wu, Ling Li, Jere Harrison

Keywords(s): Electronics & Semiconductors

Category(s): Electrical > Electronics & Semiconductors, Materials > Fabrication Technologies