Search Results - yi+xing

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Targeted Neoantigen Vaccination in H3G34R/V Glioma (UCLA Case No. 2021-008)

UCLA researchers in the Departments of Neurosurgery and Microbiology, Immunology, and Molecular Genetics have developed an immunotherapy treatment methodology for H3G34R/V high-grade glioma, providing an ability to be adapted toward a wide range of similar tumors.BACKGROUND:Over 3000 gliomas and other forms of brain cancer are diagnosed in children...

Published: 5/4/2024 | Inventor(s): Anthony Wang, Geoffrey Owens, Yi Xing, Robert Prins, Linda Liau, David Nathanson

Keywords(s): Immunotherapy, Oncology, Oncology Immunotherapy

Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy

Identification of a Platform for T Cell Receptor Recognition of Splice Variation Neoantigens in Glioblastoma (UCLA Case No. 2019-693)

UCLA researchers in the Departments of Neurosurgery and Pharmacology have developed a novel platform for the identification of alternative splice variants unique to cancer cells, for use as neo-epitope vaccines or as T cell Receptor-based cell therapy of brain cancer. BACKGROUND:T cells are a type of lymphocyte that play a central role in immune response...

Published: 5/20/2024 | Inventor(s): Robert Prins, Yi Xing

Keywords(s): Diagnostic Markers & Platforms, Oncology, Therapeutics & Vaccines

Category(s): Diagnostic Markers, Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy

IRIS: Isoform Peptides from RNA Sequencing for Immunotherapy Targets Screening

UCLA Case No. 2018-916SUMMARYResearchers led by Dr. Xing from the Department of Microbiology, Immunology, and Molecular Genetics at UCLA have developed a big data approach to identify targets for personalized cancer immunotherapy. BACKGROUNDImmunotherapies aim to use the patient’s own immune system to fight cancerous cells, but to be...

Published: 7/19/2023 | Inventor(s): Yi Xing, Yang Pan, Taegyun Yang, Yuanyuan Wang

Keywords(s):

Category(s): Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery > Nucleic Acid Platform Systems, Therapeutics > Oncology > Oncology (Small Molecules), Software & Algorithms > Data Analytics

DARTS: Deep Learning Augmented RNA-seq Analysis of Transcript Splicing

SummaryResearchers led by Yi Xing have developed a novel deep learning algorithm to detect alternative splicing patterns in RNA-seq dataBackgroundDevelopment of genetic sequencing tools like RNA-seq has ushered in an age of big data in genomics and transcriptomics. Collective efforts like ENCODE and the Roadmap Epigenomics Project (REP) have accelerated...

Published: 7/19/2023 | Inventor(s): Yi Xing, Zijun Zhang

Keywords(s): Life Science Research Tools, Nucleic Acid Platform Systems, Research Methods, Software, Targets And Assays, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Platforms > Drug Delivery > Nucleic Acid Platform Systems, Therapeutics, Software & Algorithms > Programs