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Combination Therapy Approach Using Novel Biguanides For Cancer Treatment

SummaryResearchers in the UCLA Departments of Molecular and Medical Pharmacology, Chemistry and Biochemistry, Surgery, and Medicine have developed novel metformin analogues which, when combined with immune checkpoint inhibitors, enhance the therapeutic benefit of these inhibitors in treating triple-negative breast cancer and other malignancies.BackgroundImmune...

Published: 7/19/2023 | Inventor(s): Michael Jung, Jennifer Murphy, Richard Pietras, Begonya Comin-Anduix, Diana Marquez Garban

Keywords(s): Drug Delivery, Genetic Disease, Immunotherapy, Life Science Research Tools, Medical Devices and Materials, Oncology, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Medical Devices, Platforms > Drug Delivery, Therapeutics, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy