Search Results - diagnostic+markers+%3e+aging

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2020-776 INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR (IGF-1R) BINDING PROTEINS AND METHODS OF USE
SUMMARYUCLA researchers in the Department of Pediatrics have developed inhibitors of IGF-1R that can be used to reduce the negative healthspan parameters associated with aging.BACKGROUNDHuman aging results in the continual decline of healthspan parameters spanning organ systems throughout the body. Therefore, therapeutic agents that can reverse or delay...
Published: 9/5/2023   |   Inventor(s): Pinchas Cohen
Keywords(s):  
Category(s): Diagnostic Markers > Aging, Therapeutics > Cardiovascular, Therapeutics > CNS and Neurology
2019-480: DNA Methylation Based Estimator of Telomere Length
UCLA researchers in the Department of Human Genetics and Biostatistics have developed a tool that utilizes DNA methylation biomarkers to estimate telomere length. The technology has great potential to monitor and evaluate interventions applied to age-related conditions.BACKGROUND: Telomeres are repetitive nucleotide sequences at the end of chromosomes...
Published: 7/19/2023   |   Inventor(s): Stefan Horvath
Keywords(s): Aging, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools > Research Methods, Diagnostic Markers > Aging, Platforms > Diagnostic Platform Technologies
2018-734 MITOCHONDRIAL DNA DELETION MUTATION ASSAY
INTRODUCTION:UCLA researchers in the Department of Geriatric Medicine have developed a novel method for the concurrent quantification of mitochondrial DNA content and mutation frequency in both single cells and tissue homogenates.BACKGROUND:The human mitochondrial DNA (mtDNA) genome consists of about 37 genes, all of which are essential for mitochondrial...
Published: 7/19/2023   |   Inventor(s): Jonathan Wanagat, Allen Herbst
Keywords(s): Aging, Diagnostic Markers & Platforms, Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools > Research Methods, Diagnostic Markers > Aging