Search Results - therapeutics+%3e+cardiovascular

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Stabilized Right Atrial to Pulmonary Artery Cannula for Extracorporeal Life Support (Case No. 2023-231)

Summary: UCLA researchers in the department of surgery developed a right atrial to pulmonary canula for extracorporeal life support. Background: Extracorporeal life support (ECLS) is a last-resort medical intervention designed to support patients with severe cardiac or pulmonary failure. This technology involves the diversion of blood flow to an...

Published: 10/13/2023 | Inventor(s): Peyman Benharash, Joseph Hadaya, Yas Sanaiha, Ali Nsair

Keywords(s): Advanced Life Support, blood flow management, cannula, Cardiac failure, cardiopulmonary illness, cardiovascular therapeutic solution, extracorporeal life support (ECLS), heart support, Intensive care unit (ICU), pulmonary failure, respiratory failure, right atrial to pulmonary canula

Category(s): Medical Devices, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Respiratory And Pulmonary

2022-267 Enhanced Interpretation of Cardiopulmonary Exercise Test Data

Summary: UCLA researchers in the Department of Medicine have developed a novel software that is capable of analyzing and interpreting standardized cardiopulmonary exercise data and facilitating pattern recognition and data visualization, providing users key insights from raw data. Background: A wide array of exercises exist to evaluate cardiopulmonary...

Published: 7/19/2023 | Inventor(s): Christopher Cooper, Apurva Shah

Keywords(s): Big Data, Cardiovascular, Cardiovascular Disease, Medical Device, Respiratory & Pulmonary, Software, Virtual Reality Occupational Therapy Exercise Machine

Category(s): Software & Algorithms, Software & Algorithms > Digital Health, Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > Cardiovascular, Software & Algorithms > Data Analytics

2021-189: NOVEL AND ROBUST COMBINATORY THERAPY FOR AORTIC ANEURYSMS

SUMMARY: Researchers from UCLA’s Department of Anesthesiology have developed an oral combinatory therapy that holds enormous implications in healthcare for the complete attenuation of aneurysm formation. BACKGROUND: Aortic aneurysms are abnormal protrusions in the major blood vessels from the heart to the rest of the body. These protrusions...

Published: 7/19/2023 | Inventor(s): Hua Linda Cai

Keywords(s):

Category(s): Therapeutics > Cardiovascular, Therapeutics > Hematology

2021-052 BOOST CARDIAC REPROGRAMMING BY MODULATING IMMUNE CELLS AND MICROENVIRONMENT

SUMMARYResearchers from the Department of Bioengineering at UCLA have identified key players in in both preventing and boosting cardiac reprogramming. This innovation can be used for in vivo human cardiac reprogramming to provide a novel approach for cardiac regeneration in the clinic and other fields of regenerative medicine. BACKGROUNDIschemic heart...

Published: 9/5/2023 | Inventor(s): Song Li

Keywords(s):

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base, Platforms > Drug Delivery > Viral Delivery Systems, Therapeutics, Therapeutics > Cardiovascular

2020-776 INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR (IGF-1R) BINDING PROTEINS AND METHODS OF USE

SUMMARYUCLA researchers in the Department of Pediatrics have developed inhibitors of IGF-1R that can be used to reduce the negative healthspan parameters associated with aging.BACKGROUNDHuman aging results in the continual decline of healthspan parameters spanning organ systems throughout the body. Therefore, therapeutic agents that can reverse or delay...

Published: 9/5/2023 | Inventor(s): Pinchas Cohen

Keywords(s):

Category(s): Diagnostic Markers > Aging, Therapeutics > Cardiovascular, Therapeutics > CNS and Neurology

2021-075 A New Drug Class Inhibits Illness and Death Due to Coronavirus Infection in Mice

Researchers from UCLA’s Department of Molecular and Medical Pharmacology have identified and validated a therapeutic target and an accompanying drug class which ameliorates illness and death due to Coronavirus infection. BACKGROUNDThere remains an urgent need for treatments that can reduce the symptoms for those infected by SARS-CoV-2, its future...

Published: 7/19/2023 | Inventor(s): Daniel Kaufman, Jide Tian

Keywords(s): Immunotherapy

Category(s): Therapeutics > Autoimmune, Therapeutics > Cardiovascular

2019-713 ENGINEERING A NATURALLY-DERIVED ADHESIVE AND CONDUCTIVE CARDIOPATCH

SUMMARY UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a novel material to aid in the recovery of heart attack patients. BACKGROUND Heart disease is one of the major causes of death and disability in developed countries. Incidents such as heart attacks can result in partial or complete blockage of a coronary...

Published: 7/19/2023 | Inventor(s): Nasim Annabi, Brian Walker

Keywords(s):

Category(s): Materials > Membranes, Therapeutics > Cardiovascular

2020-190 SUPPRESSION OF SOX2 IN THE TREATMENT OF VASCULAR DISEASE

SUMMARY:UCLA researchers in the department of medicine have discovered that suppressing SOX2 in the vascular endothelium improves lumen disorder thereby, inhibiting vascular calcification and cerebral arteriovenous malformations (AVMs).BACKGROUND:AVMs can form in multiple organs randomly or due to genetic diseases. AVMs have high tendencies to cause...

Published: 9/5/2023 | Inventor(s): Yucheng Yao

Keywords(s):

Category(s): Therapeutics > Cardiovascular, Therapeutics > CNS and Neurology

2020-782 FULL-LENGTH CILP AS A BIOMARKER FOR CARDIAC FIBROSIS

SUMMARY UCLA researchers in the Department of Internal Medicine, Cardiology have identified a circulating biomarker for diagnosing cardiac fibrosis. BACKGROUND Cardiac fibrosis is a pathological process associated with various forms of heart diseases that contribute to impaired heart function, development of irregular heartbeat, and ultimately heart...

Published: 7/19/2023 | Inventor(s): Reza Ardehali

Keywords(s):

Category(s): Diagnostic Markers, Therapeutics > Cardiovascular

2020-141 THERAPEUTICS TO TREAT CARDIAC ARRHYTHMIA

SUMMARYUCLA researchers in the Department of Chemistry & Biochemistry have developed novel small molecule compounds for alleviating cardiac arrhythmia. These new compounds are analogs of existing anti-arrhythmic molecule, efsevin, demonstrating enhanced anti-arrhythmic activity compared to efsevin.BACKGROUND Cardiac arrhythmias are responsible for...

Published: 9/5/2023 | Inventor(s): Ohyun Kwon

Keywords(s):

Category(s): Therapeutics > Cardiovascular

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