Search Results - platforms+%3e+diagnostic+platform+technologies

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Detection of Dicrotic Notch in Arterial Pressure and Photoplethysmography Signals Using Iterative Envelope Mean Filter (Case No. 2024-034)

Summary: UCLA Researchers in the Department of Anesthesiology have developed an iterative envelope mean (IEM) method for the detection of specific features in arterial pressure monitoring applications. Background: The cardiac cycle consists of the distinct systolic and diastolic phases. The transition from the contracted, systolic phase to the...

Published: 4/8/2024 | Inventor(s): Maxime Cannesson, Ravi Pal, Akos Rudas, Jeffrey Chiang, Sungsoo Kim

Keywords(s): arrhythmia, arterial blood pressure (ABP), cardiac cycle, Cardiac Electrophysiology, Cardiac failure, Cardiac Magnetic Resonance Imaging, cardiometabolic disease, cardiopulmonary illness, Cardiovascular, Cardiovascular Disease, Cardiovascular Disease Nephropathy, cardiovascular modeling, cardiovascular prediction, cardiovascular therapeutic solution, diastolic, diastolic phase peak, dicrotic notch, feature extraction tool, iterative envelope method (IEM), Medical Device, medical device cardiac monitoring, Medical Device Poly(Methyl Methacrylate), Medical Devices and Materials, non-invasive cardiac monitoring, photoplethysmography (PPG), Smart medical device, systolic, tachycardia, wearable medical device, wearable medical devices

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms, Platforms > Diagnostic Platform Technologies, Software & Algorithms, Diagnostic Markers > Targets And Assays, Diagnostic Markers

Field-Effect Transistor Biosensors Integrated With Porous Media (Case No. 2023-093)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering in collaboration with the University of Chicago have developed a new diagnostic biosensor by combining field-effect transistors with porous media. Background: Point-of-care (POC) and self-testing tools rely on the real-time monitoring of biomarkers in bodily fluids....

Published: 4/1/2024 | Inventor(s): Aydogan Ozcan, Hyou-Arm Joung, Hyun-June Jang, Junhong Chen

Keywords(s): Biomarker, biomarkers, Biomaterial, Biosensor, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Electrical, Electrical Engineering, electrically-mediated sensing, electrochemical sensors, enzyme functionalization, Medical diagnostics, multiplexed analysis, Point Of Care, point-of-care, porous media, sample matrix effects, transistors

Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Monitoring And Recording Systems, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms, Platforms > Diagnostic Platform Technologies

A System for Detecting Ventriculoperitoneal Shunt Failure (Case No. 2023-057)

Summary: UCLA researchers in the David Geffen School of Medicine and Department of Neurosurgery have created a novel ventriculoperitoneal shunt failure detection system that can alert patients and healthcare providers to prevent life-threatening emergencies. Background: Each year, an estimated 30,000 ventriculoperitoneal (VP) shunts are surgically...

Published: 12/19/2023 | Inventor(s): Geoffrey Colby, David Zarrin

Keywords(s): catheter, cerebrospinal fluid (CSF), CSF disorders, early alert system, elevated intracranial pressure, extraventricular drain, hydrocephalus, intracranial hypertension, intracranial pressure, neurological disorders, ventricular system, ventriculoperitoneal, ventriculoperitoneal shunt failure

Category(s): Medical Devices, Medical Devices > Surgical Tools, Medical Devices > Monitoring And Recording Systems, Platforms, Platforms > Diagnostic Platform Technologies, Electrical, Electrical > Sensors, Electrical > Instrumentation

Label-Free Optical Mapping for Large-Area Biomechanical Dynamics of Multicellular Systems (Case No. 2023-290)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel label-free optical mapping method for profiling real-time biomechanical dynamics over larger areas with high spatiotemporal resolution. Background: Mapping biomechanical dynamics often involves the use of various advanced technologies to measure...

Published: 12/20/2023 | Inventor(s): Pei Yu Chiou, Yen-Ju Lin

Keywords(s): bioimaging, Biomechanics, cell imaging, Confocal Microscopy, dye, Fluorescence Microscope, labeling, Microscopy, Microscopy And Imaging, resolution, traction force microscopy

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Cell Counting And Imaging, Medical Devices, Medical Devices > Medical Imaging, Platforms, Platforms > Diagnostic Platform Technologies

Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)

Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...

Published: 11/29/2023 | Inventor(s): Eleazar Eskin, Valerie Arboleda

Keywords(s): agnostic detection, Bioinformatics, bioinformatics pipeline, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Test, DNA Sequencing, Medical diagnostics, metagenomic diagnostic platform, meta-genomics, next generation sequencing (NGS), Pathogen, Pathogenesis, Sequencing

Category(s): Platforms, Platforms > Diagnostic Platform Technologies, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics

Wireless and Batteryless Localization and Physiological Motion Detection System (Case No. 2023-046)

Summary: UCLA researchers in the Electrical and Computer Engineering Department have developed a battery-free localization system equipped with wireless energy harvesting feature, allowing precise localization in gastrointestinal disease detection and treatment. Background: The evolution of wireless capsule endoscopy (WCE) has emerged as a convenient...

Published: 3/7/2024 | Inventor(s): Aydin Babakhani, Arkaprova Ray, Iman Habibagahi

Keywords(s): battery-less, biomedical sensors, capsule endoscope, Energy Harvesting, gastrointestinal (GI) tract diseases, implantable sensors, localization, localization accuracy, motion detection, point-of-care, wireless capsule endoscopy, wireless energy harvesting

Category(s): Electrical, Electrical > Sensors, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Platforms, Platforms > Diagnostic Platform Technologies

Core-Shell Hydrogel Particles With Tunable Porosity for Digital Nucleic Acid Assays (Case No. 2023-058)

Summary: UCLA researchers in the Department of Bioengineering have developed a novel method to perform ultra-high sensitivity, low-cost nucleic acid amplification assays utilizing porous microdroplets. Background: Nucleic acid concentration measurement is essential in biological research and diagnostics. The 2020 pandemic underscored the importance...

Published: 8/30/2023 | Inventor(s): Dino Di Carlo, Michael Thomas Alesse Bogumil

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Flow Cytometry, Medical diagnostics

Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Chemical > Emulsions, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies

2022-291: Methods for Identifying and Correcting Tumor Humoral Immune Dysfunction

UCLA researchers in the Department of Bioengineering have developed a platform advancing systems serology that profiles the Fc properties of anti-tumor antibodies (ATAbs) to provide more nuanced understanding of a cancer’s humoral immunity and better guide therapeutic approaches towards overcoming the immune dysregulation. BACKGROUND: Antibodies...

Published: 2/15/2024 | Inventor(s): Aaron Meyer

Keywords(s): antibody Fc profiling, Anti-tumor antibodies, anti-tumor immune response, ATAbs, Cancer, immune evasion, Oncology, systems serology

Category(s): Diagnostic Markers > Cancer, Platforms > Diagnostic Platform Technologies

2023-021 A Ferrobotic Swarm Technology for Accessible, Adaptable, and Automated Testing

Summary: UCLA Researchers in the Department of Electrical and Computer Engineering have developed an automated, algorithm-driven nucleic acid amplification test (NAAT) method that is easy to manufacture, distribute, and yields accurate results with reduced demand of testing reagents. Background: Major epidemics over the last two decades have emerged...

Published: 8/8/2023 | Inventor(s): Dino Di Carlo, Sam Emaminejad, Haisong Lin, Wenzhuo Yu, Kiarash AmirMozafariSabet

Keywords(s): Algorithm, algorithm-based testing, automated testing, Automation, Cell Counting/Imaging, COVID-19, Ferrofluid, ferrorobotics, high throughput testing, Nanotechnology, nucleic acid amplification test (NAAT), Nucleic Acid Platform Systems, Nucleic Acids, polymerase chain reaction (PCR), pooling, Software & Algorithms, viral testing

Category(s): Software & Algorithms, Life Science Research Tools, Life Science Research Tools > Research Methods, Electrical > Electronics & Semiconductors, Diagnostic Markers, Life Science Research Tools > Cell Counting And Imaging, Platforms > Diagnostic Platform Technologies

2022-048 Flexible Radiofrequency (RF) Coil for Small Field-Of-View Magnetic Resonance Imaging (MRI)

Summary: UCLA researchers in the Department of Neurosurgery have developed a miniature flexible radiofrequency coil for MRI for the detection of small pathological lesions. Background: Magnetic resonance imaging (MRI) is a widely-used medical imaging modality, which can produce clear and contrasted pictures of human anatomy by utilizing magnetism...

Published: 7/19/2023 | Inventor(s): Marvin Bergsneider, Robert Candler, Kyung Hyun Sung, Siyuan Liu, Jiahao Lin

Keywords(s): coil design, coil simulation, Endoscopes, endoscopic devices, endoscopic endonasal surgery, Endoscopy, High-resolution, Image Resolution, MRI, pituitary gland, pituitary microadenomas, pituitary tumors, Radio Frequency Coil Human Factors And Ergonomics, radiofrequency (RF) coil, Radiofrequency Ablation, Signal Processing, Signal-To-Noise Ratio, Simulation & Modeling, simulation model, Spatial Multiplexing, spatial resolution, Surgery

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > MRI

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