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2017-657: Gene Editing Stem Cells for Generating Non-Alloreactive T Cells for Immunotherapy
SUMMARY UCLA researchers in the Department of Pathology and Medicine have developed human stem cells that can be used to generate non-alloreactive, antigen specific T cells for adoptive cell therapy. BACKGROUND Adoptive cell therapy (ACT) with engineered T cells has shown unprecedented potential in the treatment of cancer, infectious diseases,...
Published: 9/5/2023
|
Inventor(s):
Gay Crooks
,
Christopher Seet
,
Amelie Montel Hagen
Keywords(s):
Gene Editing Systems
,
Gene Therapy
,
iPS/stem cells
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Therapeutics
,
Therapeutics > Gene Therapy And Editing
,
Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
A Method for Identifying T Cells with Specific Antigen Reactivity (UCLA Case No. 2019-546)
INTRODUCTION: UCLA researchers in the Department of Medicine have developed a novel method for the isolation of T cells reactive to specific antigens for use in cellular immunotherapy. BACKGROUND:T cell responses to proteins on antigen presenting cells is exceptionally antigen-specific. The identification of antigen-specific T cells, or the sequences...
Published: 9/19/2024
|
Inventor(s):
Christopher Seet
,
Gay Crooks
Keywords(s):
Autoimmune
,
Immunotherapy
,
Infectious Diseases
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Therapeutics > Autoimmune
,
Therapeutics > Infectious Diseases