Search Results - fluorescent+labelling

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Refractive Index-Corrected Light-Sheet Microscopy (Case No. 2025-176)

Summary: UCLA researchers from the Department of Medicine have developed a novel light-sheet fluorescence microscopy system that enables adaptive imaging across a range of refractive indices for enhanced biomedical imaging. Background: Light-sheet fluorescence microscopy (LSFM) has revolutionized biomedical imaging by allowing rapid and high-resolution...

Published: 8/15/2025 | Inventor(s): Tzung Hsiai, Enbo Zhu

Keywords(s): bioimaging, cell imaging, Fluorescence, fluorescence lifetime, Fluorescence Microscope, fluorescence microscopy, Fluorescence-Lifetime Imaging Microscopy Leading Lights, Fluorescent Labelling, Hyperspectral Imaging, immunofluorescence, Microscope, Microscopy, Microscopy And Imaging, Near-Field Scanning Optical Microscope

Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > Fluorescence, Optics & Photonics, Optics & Photonics > Microscopy, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging

2022-140 Label-Free Virtual HER2 Immunohistochemical Staining of Breast Tissue Using Deep Learning

SUMMARY: UCLA researchers in the Departments of Bioengineering and Electrical and Computer Engineering have developed a deep learning-based algorithm that can detect and quantify the breast cancer marker human epidermal growth factor receptor 2 (HER2) in microscopic images without the need for time-consuming immunohistochemical staining (IHC). BACKGROUND:...

Published: 2/14/2025 | Inventor(s): Aydogan Ozcan, Yair Rivenson, Bijie Bai, Hongda Wang

Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Biomarker, Bladder Cancer, Breast Cancer, Cancer, Cancer Immunotherapy, Computer Aided Learning, Diagnostic Markers & Platforms, Diagnostic Test, Fluorescence, Fluorescent Labelling, HER2/Neu, Histology, Immune System, Immunohistochemistry, Life Science Research Tools, Machine Learning, Optics, Research Methods, Unsupervised Learning

Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers, Diagnostic Markers > Immunology, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > Fluorescence, Software & Algorithms > Artificial Intelligence & Machine Learning, Optics & Photonics

Biocompatible, Degradable Hollow Shell Particles for High-Throughput Screening and Sorting of Cells (Case No. 2021-026)

Summary: UCLA researchers in the Department of Bioengineering have developed a microfluidic technique that can encapsulate specific cells and separate them with fluorescence cell sorters. Background: The interest in cell-derived byproducts such as recombinant therapeutic proteins and antibody therapy has increased in the past years. Typically,...

Published: 7/17/2025 | Inventor(s): Dino Di Carlo, Mark Van Zee, Joseph de Rutte, Sohyung Lee

Keywords(s): Assay, Bioassay, Cell Growth, Fluorescence, Fluorescent Labelling, High-Content Screening, High-Throughput Screening, Nanotechnology, Screening Libraries

Category(s): Life Science Research Tools, Life Science Research Tools > Screening Libraries, Life Science Research Tools > Cell Lines, Life Science Research Tools > Cell Counting And Imaging, Materials > Nanotechnology