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High-Throughput Microfluidic Gene-Editing Via Cell Deformability within Microchannels (UCLA Cases 2017-109, 2022-324)

SUMMARY UCLA researchers in the Departments of Pediatrics and Chemistry & Biochemistry have developed a microfluidic device for delivery of biomolecules into living cells using mechanical deformation, without the fouling issues in current systems. BACKGROUND Gene therapy and gene modification technologies are increasingly being studied and...

Published: 9/12/2025 | Inventor(s): Steven Jonas, Paul Weiss, Ali Khademhosseini, Joanna Aizenberg, Xu Hou

Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Genetic Disease, Life Science Research Tools, Microfluidics And Mem's, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Microfluidics And Mems, Platforms > Drug Delivery, Therapeutics, Therapeutics > Gene Therapy And Editing