Search Results - john+lee

3 Results

Sort By:

Targeting Prostate Cancer with a Novel T-Cell Receptor and Tissue-Specific Cancer Antigens for Improved Immune Response (UCLA Case No. 2022-070)

Researchers from UCLA’s Department of Microbiology, Immunology, & Molecular Genetics (MIMG), and the department of Molecular and Medical Pharmacology have identified a set of tissue-specific antigens which have been used to isolate and characterize a group of novel T-cell receptors (TCRs) which target prostate cancer specifically. Furthermore,...

Published: 11/15/2024 | Inventor(s): Owen Witte, Zhiyuan Mao, Jami Witte, Pavlo Nesterenko, John Lee

Keywords(s): Cancer, cancer antigen, Peptide, peptides, prostate cancer, protein, t-cells

Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

2015-288 TRP: Derivation of a Human Neuroendocrine Prostate Cancer Cell Line with Defined Oncogenic Drivers

Derivation Of A Human Neuroendocrine Prostate Cancer Cell Line With Defined Oncogenic DriversSUMMARYResearchers at UCLA have developed a malignant neuroendocrine prostate cancer cell line that was derived from benign human prostate tissue and transformed with the oncogenes MYCN and myristoylated AKT1.BACKGROUNDHuman cell lines are an important component...

Published: 7/19/2023 | Inventor(s): Owen Witte, John Lee

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Cell Lines

Surfaceome Profiling of Advanced Prostate Cancer to Identify Target Antigens for Immune-Based Therapy (UCLA Case. No. 2018-571)

Surfaceome Profiling Of Advanced Prostate Cancer To Identify Target Antigens For Immune-Based TherapySUMMARYDr. Witte and colleagues at UCLA have developed a novel approach to identify surface biomarkers and targetable antigens in prostate cancer by combining multiple omics analyses across different cell lines.BACKGROUNDProstate cancer is the most common...

Published: 9/19/2024 | Inventor(s): Owen Witte, John Lee, Nathanael Bangayan

Keywords(s): Life Science Research Tools, Research Methods

Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods