Search Results - peptide

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Affinity and Functional Based Screening of T Cell Receptor Repertoire Using Nanovials (Case No. 2024-042)

Summary: Researchers in the Department of Bioengineering at UCLA have developed a hydrogel platform that measures single T cell secretions, aiding in the definition of T cell receptor repertoires for functional immunotherapy applications. Background: T cell immunotherapies, namely T cell receptor (TCR) therapies, have emerged as promising candidates...

Published: 10/8/2024 | Inventor(s): Dino Di Carlo, Owen Witte, Doyeon Koo, Zhiyuan Mao

Keywords(s): Cancer Immunotherapy, CAR-T cell therapy, Flow Cytometry, hydrogel, Immunooncology, Immunotherapy, Peptide, single cell analysis, T Cell, T cell based therapy

Category(s): Diagnostic Markers > Immunology, Life Science Research Tools > Screening Libraries, Therapeutics > Immunology And Immunotherapy

Targeting Prostate Cancer with a Novel T-Cell Receptor and Tissue-Specific Cancer Antigens for Improved Immune Response (UCLA Case No. 2022-070)

Researchers from UCLA’s Department of Microbiology, Immunology, & Molecular Genetics (MIMG), and the department of Molecular and Medical Pharmacology have identified a set of tissue-specific antigens which have been used to isolate and characterize a group of novel T-cell receptors (TCRs) which target prostate cancer specifically. Furthermore,...

Published: 11/15/2024 | Inventor(s): Owen Witte, Zhiyuan Mao, Jami Witte, Pavlo Nesterenko, John Lee

Keywords(s): Cancer, cancer antigen, Peptide, peptides, prostate cancer, protein, t-cells

Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

2020-439 4F FOR AMD

Researchers at UCLA’s David Geffen School of Medicine, in collaboration with researchers from the University of Lubeck, Germany, have developed an anti-inflammatory, antiatherogenic peptide which ameliorates symptoms and progression of age-related macular degeneration (AMD) and could work to reduce the severity of other eye diseases presenting...

Published: 7/19/2023 | Inventor(s): Alan Fogelman, Mohamad Navab, Gattadahalli Anantharamaiah, Martin Rudolf

Keywords(s): Macular Degeneration, Peptide

Category(s): Platforms > Drug Delivery > Peptide Base