Search Results - neurology

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Positive Unlabeled Learning With Bias Mitigation for Fair Prediction of Undiagnosed Alzheimer’s Disease (Case No. 2025-113)

Summary: UCLA researchers in the Department of Neurology have developed a software to predict the diagnosis of Alzheimer’s Disease without racial or ethnic biases. Background: Alzheimer’s Disease (AD) represents a major health and economic challenge in the United States. Despite its prevalence, Alzheimer’s remains significantly...

Published: 2/14/2025 | Inventor(s): Timothy Chang

Keywords(s): Alzheimers disease, artificial intelligence/machine learning models, electronic health records (EHR), medical bias reduction, Neurodegeneration Alzheimer's Disease Predictive Testing, neurological disorders, Neurology, personalized medicine

Category(s): Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Data Analytics, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Software & Algorithms > Programs, Diagnostic Markers > Aging, Therapeutics > CNS and Neurology

Electrical Stimulation for Acute Stroke (Case No. 2020-787)

Summary: Researchers at the UCLA Department of Neurology have developed an individualized method of delivering non-invasive electrical stimulation to treat acute human ischemic stroke. Background: Stroke is a leading cause of mortality and morbidity across the world. Over 80% of strokes are ischemic due to blockage of blood vessels, causing a low...

Published: 2/14/2025 | Inventor(s): Mersedeh Bahr Hosseini, Jeffrey Saver, Marom Bikson

Keywords(s): Acute ischemic stroke, CNS Rehabilitation, Electrical, Electrical Engineering, Electrical stimulation, Neurocognitive, Neuroimaging, Neurointervention, neurological disorders, Neurology, Neuromodulation, Neuron, Neuropathology, Neuropsychological Test, neuroscience, Neurostimulation, Neurosurgery, soft electrical circuits, Stroke, Stroke Geriatrics Energy Accounting Local Area Network, stroke rehabilitation, stroke therapeutics, Transcutaneous Electrical Nerve Stimulation

Category(s): Electrical, Electrical > Flexible Electronics, Medical Devices, Medical Devices > Cardiac, Medical Devices > Hospital Systems

Stimulation of Parvalbumin Neurons to Enhance Recovery After Stroke (UCLA Case No. 2024-131)

UCLA researchers from the Department of Neurology have discovered a molecular compound that promotes activation of parvalbumin neurons in the brain, enhancing behavioral recovery after stroke. BACKGROUND: Stroke is a leading cause of death and disability worldwide. According to the World Health Organization, approximately 15 million people suffer from...

Published: 2/14/2025 | Inventor(s): Stanley Carmichael

Keywords(s): Cns, Neurology, neuroscience, parvalbumin neurons, spinal cord, Stroke, stroke rehabilitation, stroke therapeutics

Category(s): Therapeutics > CNS and Neurology

Intelligent Stent System for Chronic On-Demand Drug Delivery (Case No. 2021-069)

Summary: UCLA researchers in the Department of Neurology have developed an intelligent stent system for chronic on-demand drug delivery, addressing the challenge of the blood-brain barrier hindering drug therapy in the central nervous system. Background: The blood-brain barrier poses a significant obstacle to effective drug delivery to the central...

Published: 2/14/2025 | Inventor(s): Jose Morales, Haotian Lu, Huachen Cui, Xiaoyu Zheng

Keywords(s): blood flow management, blood-brain barrier, Drug, Drug Delivery, Drug monitoring, Invasiveness Of Surgical Procedures, MEMS, minimally invasive device, minimally invasive drug delivery systems, neural signals, neural stimulation, Neurocognitive, Neurodegeneration, neurological disorders, Neurology, neuro-oncology, Neuropathology, Neurosurgery, non-invasive, non-invasive drug monitoring, on-demand drug delivery, Pharmaceutical Drug, piezoelectric ultrasound transducers

Category(s): Platforms, Platforms > Drug Delivery, Medical Devices, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Oncology, Therapeutics > Musculoskeletal Disease

2020-839 Endovascular Transvascular (Transmural) Neuromodulation Technique

SUMMARY: UCLA researchers in the Department of Neurosurgery have developed an endovascular method to deliver pharmaceutical agents with various physical properties (e.g. liquids, gels, solids) across the wall of a vessel directly to the nervous system tissue. BACKGROUND: Portions of the nervous system, such as the autonomic ganglia and associated...

Published: 2/14/2025 | Inventor(s): Geoffrey Colby, Michael Dacey, Jeffrey Ardell

Keywords(s): Cardiovascular, Neurology, Neuromodulation, Neuron, Neurostimulation, Neurosurgery, Peripheral Vascular Disease

Category(s): Medical Devices > Neural Stimulation, Medical Devices > Surgical Tools