Search Results - neurology

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Stimulation of Parvalbumin Neurons to Enhance Recovery After Stroke (UCLA Case No. 2024-131)

UCLA researchers from the Department of Neurology have discovered a molecular compound that promotes activation of parvalbumin neurons in the brain, enhancing behavioral recovery after stroke. BACKGROUND: Stroke is a leading cause of death and disability worldwide. According to the World Health Organization, approximately 15 million people suffer from...

Published: 8/28/2024 | Inventor(s): Stanley Carmichael

Keywords(s): Cns, Neurology, neuroscience, parvalbumin neurons, spinal cord, Stroke, stroke rehabilitation, stroke therapeutics

Category(s): Therapeutics > CNS and Neurology

Intelligent Stent System for Chronic On-Demand Drug Delivery (Case No. 2021-069)

Summary: UCLA researchers in the Department of Neurology have developed an intelligent stent system for chronic on-demand drug delivery, addressing the challenge of the blood-brain barrier hindering drug therapy in the central nervous system. Background: The blood-brain barrier poses a significant obstacle to effective drug delivery to the central...

Published: 7/9/2024 | Inventor(s): Jose Morales, Haotian Lu, Huachen Cui, Xiaoyu (Rayne) Zheng

Keywords(s): blood flow management, blood-brain barrier, Drug, Drug Delivery, Drug monitoring, Invasiveness Of Surgical Procedures, MEMS, minimally invasive device, minimally invasive drug delivery systems, neural signals, neural stimulation, Neurocognitive, Neurodegeneration, neurological disorders, Neurology, neuro-oncology, Neuropathology, Neurosurgery, non-invasive, non-invasive drug monitoring, on-demand drug delivery, Pharmaceutical Drug, piezoelectric ultrasound transducers

Category(s): Platforms, Platforms > Drug Delivery, Medical Devices, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Oncology, Therapeutics > Musculoskeletal Disease

2020-839 Endovascular Transvascular (Transmural) Neuromodulation Technique

SUMMARY: UCLA researchers in the Department of Neurosurgery have developed an endovascular method to deliver pharmaceutical agents with various physical properties (e.g. liquids, gels, solids) across the wall of a vessel directly to the nervous system tissue. BACKGROUND: Portions of the nervous system, such as the autonomic ganglia and associated...

Published: 7/19/2023 | Inventor(s): Geoffrey Colby, Michael Dacey, Jeffrey Ardell

Keywords(s): Cardiovascular, Neurology, Neuromodulation, Neuron, Neurostimulation, Neurosurgery, Peripheral Vascular Disease

Category(s): Medical Devices > Neural Stimulation, Medical Devices > Surgical Tools